The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

Molecular imaging of pathologic lesions can improve efficient detection of cancer and
cardiovascular diseases. A shared pathophysiological feature is angiogenesis, the formation …

Introduction Stroke is a global health issue, and ischemic stroke is among the most common
strokes affecting many people worldwide. Throughout ischemic stroke, various immune cells …

Abstract Background Vascular dementia (VaD) is the accumulation of vascular lesions in the
subcortical white matter of the brain. These lesions progress and there is no direct medical …

Background Currently, there is a lack of intuitive analysis regarding the development trend,
main authors, and research hotspots in the field of cerebral arteriovenous malformation …

Cerebral small vessel disease (cSVD) constitutes a major risk factor for dementia.
Monocytes play important roles in cerebrovascular disorders. Herein, we aimed to …

Brain arteriovenous malformations (bAVMs) are abnormal vessels that are prone to rupture,
causing life-threatening intracranial bleeding. The mechanism of bAVM formation is poorly …

In large vessel occlusion stroke, recanalization to restore cerebral perfusion is essential but
not necessarily sufficient for a favorable outcome. Paradoxically, in some patients …

Microglia, the brain-resident immune cells, orchestrate neuroinflammatory responses and
are crucial in the progression of neurological diseases, including ischemic stroke (IS), which …

Stroke is the leading cause of serious, long-term disability in the United States. Each year,
approximately 795,000 people suffer a stroke. About 600,000 of these are first attacks, and …