Abstract The cytochrome P450 (P450) enzymes first attracted interest because of their
relevance to the metabolism of drugs, steroids, and carcinogens. Collectively, the 57 human …

Cytochrome P450 2A13 is an omitted brother of CYP2A6 that has an important role in the
drug metabolism of liver. Due to extrahepatic expression, it has gained less attention than …

Purpose While studies have documented gender differences by histologic type among lung
cancer patients, the effect of these differences on the health-related quality of life (HRQoL) of …

Cytochromes are proteins that catalyze electron transfer reactions of well-known metabolic
pathways and are classified in various superfamilies. The CYP, or P450, superfamily …

Objective: To evaluate the in vitro and silico antiproliferation of p-cymene, cumin aldehyde,
cuminic acid, and cuminol against human cancer cell lines (HCCLs). The sodium salt of the …

Background The aim of this study was to evaluate the association between CYP2A13
polymorphisms and lung cancer susceptibility using the HapMap database. Methods A case …

CYP2A13 Acts as the Main Metabolic CYP450s Enzyme for Activating Leonurine in Human
Bronchial Epithelial Cells - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Background: Recently, lung cancer has become the most common cause of cancer-related
death, several studies indicate that the cytochrome P450 2A13 (CYP2A13) polymorphisms …

Smoking can decrease CYP2A6-mediated nicotine clearance through downregulation of
hepatic CYP2A6. It is unknown if nicotine has similar effects on CYP2A in extrahepatic …

Exhaled breath has long been known to be composed of oxygen, carbon dioxide, nitrogen,
and water vapor. However, in recent decades, researchers have discovered exhaled breath …