Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions

N Pondeljak, L Lugović-Mihić, L Tomić, E Parać… - International Journal of …, 2023 - mdpi.com
The epidermis serves many vital roles, including protecting the body from external
influences and healing eventual injuries. It is maintained by an incredibly complex and …

[HTML][HTML] Emerging diagnostic and therapeutic challenges for skin fibrosis in systemic sclerosis

D Abraham, A Lescoat, R Stratton - Molecular Aspects of Medicine, 2024 - Elsevier
Systemic sclerosis (also called scleroderma, SSc) is a chronic autoimmune disorder
characterized by excessive collagen deposition leading to skin fibrosis and various internal …

Constructing epidermal rete ridges using a composite hydrogel to enhance multiple signaling pathways for the maintenance of epidermal stem cell niche

Z Shen, Z Liu, L Sun, M Li, L Han, J Wang, X Wu… - Acta Biomaterialia, 2023 - Elsevier
The undulating microstructure rete ridge (RR) located at the junction between the dermis
and epidermis plays a crucial role in improving skin mechanical properties and maintaining …

[HTML][HTML] Emergence and properties of adult mammalian epidermal stem cells

PS Gadre, P Markova, M Ebrahimkutty, Y Jiang… - Developmental …, 2024 - Elsevier
In this review we discuss how the mammalian interfollicular epidermis forms during
development, maintains homeostasis, and is repaired following wounding. Recent studies …

Controlling Cell Interactions with DNA Directed Assembly

K Mathis, CTY Chan, B Meckes - Advanced Healthcare …, 2024 - Wiley Online Library
The creation of complex cellular environments is critical to mimicking tissue environments
that will play a critical role in next‐generation tissue engineering, stem cell programming …

Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes

FM Watt, S Zijl, T Hiratsuka, A Mobasseri… - bioRxiv, 2024 - biorxiv.org
Differentiation of cultured human epidermal stem cells is regulated by interactions with the
underlying substrate. Whereas differentiation is typically stimulated when keratinocytes are …