Pain is a complex experience that involves physical, emotional, and cognitive aspects. This
review focuses specifically on the physiological processes underlying pain perception, with …

Activation of the sensory nerve ion channel TRPA1 by electrophiles is the key mechanism
that initiates nociceptive signaling, and leads to defensive reflexes and avoidance …

Abstract Charcot–Marie‐Tooth type 2A (CMT2A) is an inherited sensorimotor neuropathy
associated with mutations within the Mitofusin 2 (MFN2) gene. These mutations impair …

Regeneration failure after spinal cord injury (SCI) results in part from the lack of a pro-
regenerative response in injured neurons, but the response to SCI has not been examined …

The cornea has the densest sensory innervation of the body, originating primarily from
neurons in the trigeminal ganglion. The basic principles of cornea nerve patterning have …

Introduction Peripheral sensory neurons serve as the initial responders to the external
environment. How these neurons react to different sensory stimuli, such as mechanical or …

Abstract The ATP-sensitive P2X2 ionotropic receptor plays a critical role in a number of
signal processes including taste and hearing, carotid body detection of hypoxia, the exercise …

Abstract Charcot–Marie–Tooth disease type 2A (CMT2A), arising from mitofusin 2 (MFN2)
gene mutations, is the most common inherited axonal neuropathy affecting motor and …

Breast cancer is one of the leading causes of mortality among women. The tumour
microenvironment, consisting of host cells and extracellular matrix, has been increasingly …

Optogenetics has emerged as an important tool in neuroscience, especially in central
nervous system research. It allows for the study of the brain's highly complex network with …