Psoriasis is a chronic systemic inflammatory disease causing erythematosus and scaly skin
plaques; up to 30% of patients with psoriasis develop Psoriatic Arthritis (PsA), which is …

IL‐38 belongs to the IL‐36 cytokines, which in turn are part of the IL‐1 family. The first
biological function of IL‐38 described was blocking the activation of the IL‐36R signaling …

Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues
and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory …

Pyroptosis is a newly discovered programmed cell death with inflammasome formation.
Pattern recognition receptors that identify repetitive motifs of prospective pathogens such as …

The interleukin (IL)-1 family of cytokines is composed of 11 members, including the most
recently discovered IL-36α, β, γ, IL-37, and IL-38. Similar to IL-1, IL-36 cytokines are initiators …

This review examines the role of interleukin (IL)-38 in health and disease. IL-38 functions as
an anti-inflammatory cytokine in the IL-1 family, with properties comparable to IL-37, another …

There has been no report investigating the role of IL-38 in inflammatory bowel diseases
(IBD). Therefore, we investigated the expression of IL-38 in IBD patients and its role in …

IL-38 is the most recently discovered cytokine of the IL-1 family and is considered a potential
inhibitor of the IL-1 and Toll-like receptor families. IL-38 exerts anti-inflammatory properties …

Abstract Naturally occurring CD4+ CD25+ regulatory T cells (Tregs) are required to limit
immune‐induced pathology and to maintain homeostasis during the early‐phase of sepsis …

Context Thyroid-associated ophthalmopathy (TAO) is an organ-specific autoimmune
disease closely associated with Graves' disease. IL-38, a novel cytokine in the IL-1 …