[HTML][HTML] The Paneth cell: the curator and defender of the immature small intestine

SR Lueschow, SJ McElroy - Frontiers in immunology, 2020 - frontiersin.org
Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef
Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their …

[HTML][HTML] Potential mechanisms linking food-derived microRNAs, gut microbiota and intestinal barrier functions in the context of nutrition and human health

E Díez-Sainz, S Lorente-Cebrián, P Aranaz… - Frontiers in …, 2021 - frontiersin.org
MicroRNAs (miRNAs) are non-coding single-stranded RNA molecules from 18 to 24
nucleotides that are produced by prokaryote and eukaryote organisms, which play a crucial …

[HTML][HTML] Drinking alkaline mineral water confers diarrhea resistance in maternally separated piglets by maintaining intestinal epithelial regeneration via the brain …

J Chen, BC Zhao, XY Dai, YR Xu, JX Kang… - Journal of Advanced …, 2023 - Elsevier
Introduction Diarrhea has the fourth-highest mortality rate of all diseases and causes a large
number of infant deaths each year. The maternally separated (MS) piglet (newly weaned …

Acute exposure to fipronil induces oxidative stress, apoptosis and impairs epithelial homeostasis in the midgut of the stingless bee Partamona helleri Friese …

CF Farder-Gomes, KM Fernandes… - Science of the Total …, 2021 - Elsevier
Partamona helleri is an important pollinator in natural and agricultural ecosystems in the
neotropics. However, the foraging activity of this bee increases its risk of exposure to …

[HTML][HTML] Activation of Wnt signaling by amniotic fluid stem cell-derived extracellular vesicles attenuates intestinal injury in experimental necrotizing enterocolitis

B Li, C Lee, JS O'Connell, L Antounians, N Ganji… - Cell death & …, 2020 - nature.com
Necrotizing enterocolitis (NEC) is a devastating intestinal disease primarily affecting preterm
neonates and causing high morbidity, high mortality, and huge costs for the family and …

[HTML][HTML] Transmissible gastroenteritis virus targets Paneth cells to inhibit the self-renewal and differentiation of Lgr5 intestinal stem cells via Notch signaling

A Wu, B Yu, K Zhang, Z Xu, D Wu, J He, J Luo… - Cell death & …, 2020 - nature.com
Infection with transmissible gastroenteritis virus (TGEV) has been associated with villous
atrophy within 48 h, which seriously disrupts intestinal homeostasis. However, the …

l-Malic Acid Facilitates Stem Cell-Driven Intestinal Epithelial Renewal through the Amplification of β-Catenin Signaling by Targeting Frizzled7 in Chicks

Y Zhang, F Li, Z Lu, X Wang, H Yan… - Journal of Agricultural …, 2023 - ACS Publications
l-Malic acid (l-MA) contributes to energy metabolism and nutrient digestion, which is an
alternative to antibiotics for livestock; however, it is not clear whether l-MA can replace …

Beneficial effects of butyrate in intestinal injury

J Liu, H Zhu, B Li, C Lee, M Alganabi, S Zheng… - Journal of pediatric …, 2020 - Elsevier
Purpose Butyrate is a short-chain fatty acid produced in the intestine. It is controversial
whether butyrate is protective or destructive for the intestinal epithelium in the development …

[HTML][HTML] Necrotizing enterocolitis: LPS/TLR4-induced crosstalk between canonical TGF-β/Wnt/β-catenin pathways and PPARγ

A Gomart, A Vallée, Y Lecarpentier - Frontiers in Pediatrics, 2021 - frontiersin.org
Necrotizing enterocolitis (NEC) represents one of the major causes of morbidity and
mortality in premature infants. Several recent studies, however, have contributed to a better …

[HTML][HTML] Small extracellular vesicles from human amniotic fluid samples as promising theranostics

A Costa, R Quarto, S Bollini - International Journal of Molecular Sciences, 2022 - mdpi.com
Since the first evidence that stem cells can provide pro-resolving effects via paracrine
secretion of soluble factors, growing interest has been addressed to define the most ideal …