Space agencies are working to establish a permanent human presence on the moon and to
reach Mars within the next few decades. In these missions, astronaut crew members will be …

Infantile-and childhood-onset parkinsonism is mainly due to genetic alterations and is an
exceedingly rare condition, unlike Parkinson's disease (PD), which is one of the most …

Dominant GNAO1 mutations cause an emerging group of childhood-onset neurological
disorders characterized by developmental delay, intellectual disability, movement disorders …

Background and Objectives Identification of individuals at high risk of developing Parkinson
disease (PD) several years before diagnosis is crucial for developing treatments to prevent …

Inborn errors of metabolism (IEM) are individually rare, but collectively numerous. The
application of tandem mass spectrometry (tandem MS) to newborn screening and prenatal …

Introduction Sixteen subjects with biallelic WARS2 variants encoding the tryptophanyl
mitochondrial aminoacyl-tRNA synthetase, presenting with a neonatal-or infantile-onset …

Abstract Purpose of Review Overwhelming evidence indicates that mitochondrial
dysfunction is a central factor in Parkinson's disease (PD) pathophysiology. This paper aims …

Abstract Aminoacyl-transfer RiboNucleic Acid synthetases (ARSs) are essential enzymes
that catalyze the attachment of each amino acid to their cognate tRNAs. Mitochondrial ARSs …

Despite implementation of enhanced management practices, chronic wasting disease in US
white-tailed deer (Odocoileus virginianus) continues to expand geographically. Herein, we …

The pseudorabies virus (PRV) is identified as a double-helical DNA virus responsible for
causing Aujeszky's disease, which results in considerable economic impacts globally. The …