Nutrition and metabolic adaptations in physiological and complicated pregnancy: focus on obesity and gestational diabetes

S Parrettini, A Caroli, E Torlone - Frontiers in endocrinology, 2020 - frontiersin.org
Pregnancy offers a window of opportunity to program the future health of both mothers and
offspring. During gestation, women experience a series of physical and metabolic …

The biomedical uses of inositols: A nutraceutical approach to metabolic dysfunction in aging and neurodegenerative diseases

AJ López-Gambero, C Sanjuan, PJ Serrano-Castro… - Biomedicines, 2020 - mdpi.com
Inositols are sugar-like compounds that are widely distributed in nature and are a part of
membrane molecules, participating as second messengers in several cell-signaling …

Inositol and non-alcoholic fatty liver disease: a systematic review on deficiencies and supplementation

A Pani, R Giossi, D Menichelli, VA Fittipaldo, F Agnelli… - Nutrients, 2020 - mdpi.com
Liver lipid accumulation is a hallmark of non-alcoholic fatty liver disease (NAFLD), broadly
associated with insulin resistance. Inositols (INS) are ubiquitous polyols implied in many …

From prediabetes to type 2 diabetes mellitus in women with polycystic ovary syndrome: lifestyle and pharmacological management

A Pani, I Gironi, G Di Vieste, E Mion… - International Journal …, 2020 - Wiley Online Library
Aims. Despite the very clear association between polycystic ovary syndrome (PCOS) and
dysglycemia, few studies have explored the continuum of glycemic alterations leading from …

Thyroid dysfunction during gestation and gestational diabetes mellitus: a complex relationship

S Pinto, L Croce, L Carlier, E Cosson… - Journal of …, 2023 - Springer
Purpose Gestational diabetes mellitus (GDM) and thyroid dysfunction during gestation
(GTD) are the two most prevalent endocrinopathies during pregnancy. The aim of the …

Myoinositol reduces inflammation and oxidative stress in human endothelial cells exposed in vivo to chronic hyperglycemia

MPA Baldassarre, P Di Tomo, G Centorame, A Pandolfi… - Nutrients, 2021 - mdpi.com
Myo-inositol (Myo) improves insulin resistance, glucose metabolism, and helps gestational
diabetes (GDM) management. GDM is associated with a pro-inflammatory state and …

A review of the role of inositols in conditions of insulin dysregulation and in uncomplicated and pathological pregnancy

OC Watkins, HEJ Yong, N Sharma… - Critical Reviews in Food …, 2022 - Taylor & Francis
Inositols, a group of 6-carbon polyols, are highly bioactive molecules derived from diet and
endogenous synthesis. Inositols and their derivatives are involved in glucose and lipid …

Inositol and antioxidant supplementation: Safety and efficacy in pregnancy

G Formoso, MPA Baldassarre… - Diabetes/metabolism …, 2019 - Wiley Online Library
Pregnancies complicated by diabetes have largely increased in number over the last 50
years. Pregnancy is characterized by a physiologic increase in insulin resistance, which …

A nutritional supplement taken during preconception and pregnancy influences human milk macronutrients in women with overweight/obesity and gestational …

SM Han, JGB Derraik, MH Vickers, S Devaraj… - Frontiers in …, 2023 - frontiersin.org
Rational Maternal overweight/obesity and gestational diabetes mellitus (GDM) are
associated with an increased risk of their offspring developing overweight/obesity or type 2 …

Gestational diabetes mellitus: Prevention, diagnosis and treatment. A fresh look to a busy corner

G Zito, L Della Corte, P Giampaolino… - Journal of neonatal …, 2020 - content.iospress.com
BACKGROUND: Gestational diabetes mellitus (GDM) is a common pregnancy complication
characterized by hyperglycaemia with onset or first recognition during pregnancy. Risk …