Cancer resistance to immunotherapy: comprehensive insights with future perspectives
SS Said, WN Ibrahim - Pharmaceutics, 2023 - mdpi.com
Cancer immunotherapy is a type of treatment that harnesses the power of the immune
systems of patients to target cancer cells with better precision compared to traditional …
systems of patients to target cancer cells with better precision compared to traditional …
Plants as a source of anticancer agents: From bench to bedside
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …
Black Cumin Seed (Nigella sativa) in Inflammatory Disorders: Therapeutic Potential and Promising Molecular Mechanisms
HK Rashwan, S Mahgoub, NZ Abuelezz… - Drugs and Drug …, 2023 - mdpi.com
Inflammation is an essential defense mechanism against harmful stimuli. However,
uncontrolled inflammatory mechanisms culminate in disturbed responses that contribute to …
uncontrolled inflammatory mechanisms culminate in disturbed responses that contribute to …
Investigation of the anticancer effect of newly synthesized palladium conjugate Schiff base metal complexes on non-small cell lung cancer cell line and mouse …
B Demirbağ, K Büyükafşar, H Kaya, M Yıldırım… - Biochemical and …, 2024 - Elsevier
Lung cancer remains one of the leading causes of death worldwide. Due to the side effects
of chemotherapeutic agents on normal cells and the development of resistance by cancer …
of chemotherapeutic agents on normal cells and the development of resistance by cancer …
Gene expression profiling and protein analysis reveal suppression of the C-Myc oncogene and inhibition JAK/STAT and PI3K/AKT/mTOR signaling by thymoquinone …
Overexpression of c-Myc plays an essential role in leukemogenesis and drug resistance,
making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is …
making c-Myc an attractive target for cancer therapy. However, targeting c-Myc directly is …
Thymoquinone potentially modulates the expression of key onco-and tumor suppressor miRNAs in prostate and colon cancer cell lines: Insights from PC3 and HCT-15 …
SM Osorio-Pérez, C Estrada-Meza, LM Ruiz-Manriquez… - Genes, 2023 - mdpi.com
Prostate cancer (PC) and colon cancer significantly contribute to global cancer-related
morbidity and mortality. Thymoquinone (TQ), a naturally occurring phytochemical found in …
morbidity and mortality. Thymoquinone (TQ), a naturally occurring phytochemical found in …
Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer
F Sheikhnia, V Rashidi, H Maghsoudi… - Cancer cell …, 2023 - Springer
Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide.
Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional …
Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional …
[HTML][HTML] Thymoquinone induces downregulation of BCR-ABL/JAK/STAT pathway and apoptosis in K562 leukemia cells
Objective: BCR ABL oncogene encodes the BCR-ABL chimeric protein, which is a
constitutively activated non-receptor tyrosine kinase. The BCR-ABL oncoprotein is a key …
constitutively activated non-receptor tyrosine kinase. The BCR-ABL oncoprotein is a key …
Thymoquinone Inhibits Growth of Acute Myeloid Leukemia Cells through Reversal SHP-1 and SOCS-3 Hypermethylation: In Vitro and In Silico Evaluation
Epigenetic silencing of tumor suppressor genes (TSGs) plays an essential role in cancer
pathogenesis, including acute myeloid leukemia (AML). All of SHP-1, SOCS-1, and SOCS-3 …
pathogenesis, including acute myeloid leukemia (AML). All of SHP-1, SOCS-1, and SOCS-3 …
Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells
HA Alshwyeh, WMS Al-Sheikh, A Rasedee… - Molecular & Cellular …, 2024 - Taylor & Francis
In this study, we investigated the effects of an ethanolic extract of Mangifera indica L. kernel
on the viability and proliferation of human lung cancer cells. We utilized MTT and BrdU cell …
on the viability and proliferation of human lung cancer cells. We utilized MTT and BrdU cell …