Advanced design and applications of digital microfluidics in biomedical fields: An update of recent progress

C Yang, X Gan, Y Zeng, Z Xu, L Xu, C Hu, H Ma… - Biosensors and …, 2023 - Elsevier
Significant breakthroughs have been made in digital microfluidic (DMF)-based technologies
over the past decades. DMF technology has attracted great interest in bioassays depending …

Micro-magnetofluidics in microfluidic systems: A review

RJ Yang, HH Hou, YN Wang, LM Fu - Sensors and Actuators B: Chemical, 2016 - Elsevier
Ferrofluids have many traditional applications in the electrical, mechanical and optical fields,
including transformers, dampers, imaging systems, and so on. However, in more recent …

Highly sensitive and automated surface enhanced Raman scattering-based immunoassay for H5N1 detection with digital microfluidics

Y Wang, Q Ruan, ZC Lei, SC Lin, Z Zhu… - Analytical …, 2018 - ACS Publications
Digital microfluidics (DMF) is a powerful platform for a broad range of applications,
especially immunoassays having multiple steps, due to the advantages of low reagent …

Combining sensors and actuators with electrowetting-on-dielectric (EWOD): advanced digital microfluidic systems for biomedical applications

Z Tong, C Shen, Q Li, H Yin, H Mao - Analyst, 2023 - pubs.rsc.org
The concept of digital microfluidics (DMF) enables highly flexible and precise droplet
manipulation at a picoliter scale, making DMF a promising approach to realize integrated …

Rapid and sensitive detection of antibiotic resistance on a programmable digital microfluidic platform

S Kalsi, M Valiadi, MN Tsaloglou, L Parry-Jones… - Lab on a Chip, 2015 - pubs.rsc.org
The widespread dissemination of CTX-M extended spectrum β-lactamases among
Escherichia coli bacteria, both in nosocomial and community environments, is a challenge …

Miniaturized sample preparation on a digital microfluidics device for sensitive bottom-up microproteomics of mammalian cells using magnetic beads and mass …

J Leipert, A Tholey - Lab on a Chip, 2019 - pubs.rsc.org
While LC-MS-based proteomics with high nanograms to micrograms of total protein has
become routine, the analysis of samples derived from low cell numbers is challenged by …

Microfluidic magnetic analyte delivery technique for separation, enrichment, and fluorescence detection of ultratrace biomarkers

J Yang, X Xiao, L Xia, G Li, L Shui - Analytical Chemistry, 2021 - ACS Publications
A microfluidic magnetic analyte delivery (μMAD) technique was developed to realize sample
preparation and ultrasensitive biomarker detection. A simply designed microfluidic device …

Circle-to-circle amplification on a digital microfluidic chip for amplified single molecule detection

M Kühnemund, D Witters, M Nilsson, J Lammertyn - Lab on a Chip, 2014 - pubs.rsc.org
We demonstrate a novel digital microfluidic nucleic acid amplification concept which is
based on padlock probe mediated DNA detection and isothermal circle-to-circle …

The power of solid supports in multiphase and droplet-based microfluidics: towards clinical applications

M Serra, D Ferraro, I Pereiro, JL Viovy, S Descroix - Lab on a Chip, 2017 - pubs.rsc.org
Multiphase and droplet microfluidic systems are growing in relevance in bioanalytical-
related fields, especially due to the increased sensitivity, faster reaction times and lower …

Digital microfluidic platform for the detection of rubella infection and immunity: a proof of concept

AHC Ng, M Lee, K Choi, AT Fischer… - Clinical …, 2015 - academic.oup.com
BACKGROUND Whereas disease surveillance for infectious diseases such as rubella is
important, it is critical to identify pregnant women at risk of passing rubella to their offspring …