Molecular pathogenesis of Chlamydia trachomatis

B Jury, C Fleming, WM Huston… - Frontiers in Cellular and …, 2023 - frontiersin.org
Chlamydia trachomatis is a strict intracellular human pathogen. It is the main bacterial cause
of sexually transmitted infections and the etiologic agent of trachoma, which is the leading …

Zoonotic and other veterinary chlamydiae–an update, the role of the plasmid and plasmid-mediated transformation

H Marti, K Shima, S Boutin, J Rupp… - Pathogens and …, 2024 - academic.oup.com
The obligate intracellular bacterial genus Chlamydia harbours species with zoonotic
potential, particularly C. psittaci, causative agent of psittacosis, and C. abortus, which may …

Identification of the alternative sigma factor regulons of Chlamydia trachomatis using multiplexed CRISPR interference

ND Hatch, SP Ouellette - Msphere, 2023 - Am Soc Microbiol
Chlamydia trachomatis is a developmentally regulated, obligate intracellular bacterium that
encodes three sigma factors: σ66, σ54, and σ28. σ66 is the major sigma factor controlling …

A member of an ancient family of bacterial amino acids transporters contributes to Chlamydia nutritional virulence and immune evasion

A Banerjee, Y Sun, MK Muramatsu, E Toh… - Infection and …, 2023 - Am Soc Microbiol
Many obligate intracellular bacteria, including members of the genus Chlamydia, cannot
synthesize a variety of amino acids de novo and acquire these from host cells via largely …

The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners

CM Herrera, E McMahon, DL Swaney… - Microbiology …, 2024 - Am Soc Microbiol
Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infections in the
USA and of preventable blindness worldwide. This obligate intracellular pathogen replicates …

[图书][B] Genetic Dissection of Chlamydia spp. Determinants of Tissue Tropism, Stress Response and Nutrient Acquisition

A Banerjee - 2023 - search.proquest.com
Chlamydia trachomatis (CT) is an obligate intracellular bacterium that transitions between
two distinct morphological forms during its complex developmental cycle. During the …

Can't live outside you: a thematic issue on obligate intracellular bacterial pathogens

J Coers, HJ Newton, JA Carlyon - Pathogens and Disease, 2021 - academic.oup.com
To establish their niches for microbial replication, obligate intracellular bacterial pathogens
co-opt numerous host cell resources and hijack metabolic pathways. Because of their …

[图书][B] Elucidating the role of cholesterol during Chlamydia infection using the novel anti-chlamydial inhibitor, H89

KJ Muñoz - 2022 - search.proquest.com
Two unanswered questions in the field of Chlamydia are 1) How does the inclusion grow
over time? and 2) What promotes RB-to-EB conversion? Small molecule compounds have …

Understanding the Impact of Chlamydia Trachomatis Infection on Host Vesicular Trafficking

LM Jorgenson - 2021 - digitalcommons.unmc.edu
Chlamydia trachomatis is a highly evolved obligate intracellular bacterial pathogen. During
infection, organisms reside within a host epithelial cell in a membrane-bound vacuole called …