Generation of Functioning Platelets from Mature Megakaryocytes Derived from CD34+ Umbilical Cord Blood Cells

Z Zhong, C Chen, N Wang, Y Qiu, X Li… - Stem Cells and …, 2024 - liebertpub.com
Clinically patients with thrombocytopenia are in urgent need of platelet transfusion, thus it is
necessary to produce the platelets in large scale in vitro to meet the clinical needs. In this …

Establishment of a mouse thrombocytopenia model induced by cyclophosphamide

H Nie, K Li, X Zhang, X Feng, D Yang, Y Wu, J Zhou… - 2010 - utoronto.scholaris.ca
An experiment was conducted to compare the effects of two mouse thrombocytopenia
models induced by cyclophosphamide at two different administration routes to determine a …

环磷酰胺诱导小鼠血小板减少症模型的建立(英文)

聂红, 李孔燕, 张晓琦, 冯雪莹, 杨端容, 吴玉斯… - 动物学研究, 2009 - zoores.ac.cn
比较由环磷酰胺两种不同给药方式诱导小鼠血小板减少症模型的效果, 并对效果较稳定的一种给
药方式进行最佳造模剂量摸索, 以期确定一个造模效果较好, 毒副作用较低 …

Effects of Gonadotropins on Blood, Bone Marrow, and Spleen in Cyclophosphamide-Exposed Rats: Cyclophosphamide and Gonadotropins

BÜ Koluman, ÇİL Nazlı, GA Mete - Indian Journal of Experimental …, 2023 - or.niscpr.res.in
Cyclophosphamide (CTX) is an effective chemotherapeutic agent. Gonadotropins are
molecules with various actions. We investigated the effects of gonadotropins on the …

Experimental models of thrombocytopenia in laboratory animals and their application in identifying the complications of chemotherapy drugs

H Kamali, MR Khazaei, E Shobeiri… - Journal of Babol university …, 2018 - jbums.org
BACKGROUND AND OBJECTIVE: Thrombocytopenia is one of the complications of
chemotherapy drugs that may cause death. Different animal models of thrombocytopenia …

Effect of gonadotropins on blood, bone marrow and spleen in cyclophosphamide exposed rats

BÜ Koluman, N Çil, GA Mete - 2023 - nopr.niscpr.res.in
Cyclophosphamide (CTX) is an effective chemotherapeutic agent. Gonadotropins are
molecules with various actions. Here, we investigated the effects of gonadotropins on the …

Secretion Expression and Activity Assay of a Novel Fusion Protein of Thrombopoietin and Interleukin-6 in Pichia pastoris

H Zhiyi, L Wenshan, Z Wenze, D Ning… - Journal of …, 2007 - academic.oup.com
Thrombopoietin (TPO) is an important haematopoietic factor in megakaryocytic activities as
well as in platelet production. Interleukin 6 (IL-6) can co-stimulate TPO-dependent formation …

مدل های تجربی ایجاد ترومبوسیتوپنی درحیوانات آزمایشگاهی و کاربرد آنها در شناسایی عوارض داروهای شیمی درمانی

کمالی, خزاعی, محمدرسول, شبیری, خزاعی, مظفر - مجله علمی دانشگاه علوم …, 2018‎ - jbums.org
سابقه و هدف: ترومبوسیتوپنی از عوارض داروهای شیمی درمانی، می باشد که می تواند باعث مرگ شود.
مدل های مختلف حیوانی ترومبوسیتوپنی برای تحقیقات بالینی و شناسایی عوامل ایجاد کننده آن …