Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Brain plasticity-based therapeutics

MM Merzenich, TM Van Vleet… - Frontiers in human …, 2014 - frontiersin.org
The primary objective of this review article is to summarize how the neuroscience of brain
plasticity, exploiting new findings in fundamental, integrative and cognitive neuroscience, is …

Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease

GM Petzinger, BE Fisher, S McEwen, JA Beeler… - The Lancet …, 2013 - thelancet.com
Exercise interventions in individuals with Parkinson's disease incorporate goal-based motor
skill training to engage cognitive circuitry important in motor learning. With this exercise …

Dyskinesia in Parkinson's disease: mechanisms and current non‐pharmacological interventions

R Heumann, R Moratalla, MT Herrero… - Journal of …, 2014 - Wiley Online Library
Dopamine replacement therapy in Parkinson's disease is associated with several unwanted
effects, of which dyskinesia is the most disabling. The development of new therapeutic …

Exercise effects on brain and behavior in healthy mice, Alzheimer's disease and Parkinson's disease model—A systematic review and meta-analysis

TM da Costa Daniele, PFC de Bruin… - Behavioural brain …, 2020 - Elsevier
This systematic review and meta-analysis examines how exercise modifies brain and
behavior in healthy mice, dementia (D) and Parkinson disease (PD) models. A search was …

Neuroprotective effects of endurance exercise against neuroinflammation in MPTP-induced Parkinson's disease mice

Y Jang, JH Koo, I Kwon, EB Kang, HS Um, H Soya… - Brain Research, 2017 - Elsevier
Parkinson's disease (PD) is one of the main degenerative neurological disorders
accompanying death of dopaminergic neurons prevalent in aged population. Endurance …

The benefits of exercise on structural and functional plasticity in the rodent hippocampus of different disease models

AR Patten, SY Yau, CJ Fontaine, A Meconi… - Brain …, 2015 - content.iospress.com
In this review, the benefits of physical exercise on structural and functional plasticity in the
hippocampus are discussed. The evidence is clear that voluntary exercise in rats and mice …

Treadmill exercise produces neuroprotective effects in a murine model of Parkinson's disease by regulating the TLR2/MyD88/NF-κB signaling pathway

JH Koo, YC Jang, DJ Hwang, HS Um, NH Lee, JH Jung… - Neuroscience, 2017 - Elsevier
Parkinson's disease (PD) is characterized by progressive dopamine depletion and a loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc). Treadmill exercise is a …

Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models

EK Crowley, YM Nolan, AM Sullivan - Progress in Neurobiology, 2019 - Elsevier
Parkinson's disease (PD) is characterised by degeneration of dopaminergic neurons of the
nigrostriatal pathway, which leads to the cardinal motor symptoms of the disease-tremor …

[HTML][HTML] Exercise protects synaptic density in a rat model of Parkinson's disease

KH Binda, TP Lillethorup, CC Real, SL Bærentzen… - Experimental …, 2021 - Elsevier
Background Parkinson's disease (PD) is characterized by Lewy body and neurite pathology
associated with dopamine terminal dysfunction. Clinically, it is associated with motor …