The IMG/M data management and analysis system v. 7: content updates and new features

IMA Chen, K Chu, K Palaniappan, A Ratner… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Integrated Microbial Genomes & Microbiomes system (IMG/M: https://img. jgi.
doe. gov/m/) at the Department of Energy (DOE) Joint Genome Institute (JGI) continues to …

[HTML][HTML] Integrating statistical and visual analytic methods for bot identification of health-related survey data

AT Chen, M Komi, S Bessler, SP Mikles… - Journal of Biomedical …, 2023 - Elsevier
Objective In recent years, we have increasingly observed issues concerning quality of online
information due to misinformation and disinformation. Aside from social media, there is …

Clustergrammer, a web-based heatmap visualization and analysis tool for high-dimensional biological data

NF Fernandez, GW Gundersen, A Rahman, ML Grimes… - Scientific data, 2017 - nature.com
Most tools developed to visualize hierarchically clustered heatmaps generate static images.
Clustergrammer is a web-based visualization tool with interactive features such as: zooming …

Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling

AMP Schieber, YM Lee, MW Chang, M Leblanc… - Science, 2015 - science.org
Infections and inflammation can lead to cachexia and wasting of skeletal muscle and fat
tissue by as yet poorly understood mechanisms. We observed that gut colonization of mice …

shinyheatmap: Ultra fast low memory heatmap web interface for big data genomics

BB Khomtchouk, JR Hennessy, C Wahlestedt - PloS one, 2017 - journals.plos.org
Background Transcriptomics, metabolomics, metagenomics, and other various next-
generation sequencing (-omics) fields are known for their production of large datasets …

Diet transition from high-forage to high-concentrate alters rumen bacterial community composition, epithelial transcriptomes and ruminal fermentation parameters in …

SC Ramos, CD Jeong, LL Mamuad, SH Kim, SH Kang… - Animals, 2021 - mdpi.com
Simple Summary Cattle are fed a high-concentrate diet to improve their productivity;
however, it alters the rumen ecosystem due to high structural carbohydrates level, resulting …

MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles

QX Xuan Lin, S Sian, O An, D Thieffry… - Nucleic acids …, 2019 - academic.oup.com
Several recent studies have portrayed DNA methylation as a new player in the recruitment of
transcription factors (TF) within chromatin, highlighting a need to connect TF binding sites …

MetaCoMET: a web platform for discovery and visualization of the core microbiome

Y Wang, L Xu, YQ Gu, D Coleman-Derr - Bioinformatics, 2016 - academic.oup.com
Motivation: A key component of the analysis of microbiome datasets is the identification of
OTUs shared between multiple experimental conditions, commonly referred to as the core …

IMG-ABC: new features for bacterial secondary metabolism analysis and targeted biosynthetic gene cluster discovery in thousands of microbial genomes

M Hadjithomas, IMA Chen, K Chu, J Huang… - Nucleic Acids …, 2017 - academic.oup.com
Secondary metabolites produced by microbes have diverse biological functions, which
makes them a great potential source of biotechnologically relevant compounds with …

Haplotype-resolved genomes of geminivirus-resistant and geminivirus-susceptible African cassava cultivars

JE Kuon, W Qi, P Schläpfer, M Hirsch-Hoffmann… - BMC biology, 2019 - Springer
Background Cassava is an important food crop in tropical and sub-tropical regions
worldwide. In Africa, cassava production is widely affected by cassava mosaic disease …