Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Arginase as a potential biomarker of disease progression: a molecular imaging perspective

G S. Clemente, A van Waarde, I F. Antunes… - International Journal of …, 2020 - mdpi.com
Arginase is a widely known enzyme of the urea cycle that catalyzes the hydrolysis of L-
arginine to L-ornithine and urea. The action of arginase goes beyond the boundaries of …

Alkaline Phosphatase-Instructed Self-Assembly of Gadolinium Nanofibers for Enhanced T2-Weighted Magnetic Resonance Imaging of Tumor

L Dong, J Qian, Z Hai, J Xu, W Du, K Zhong… - Analytical …, 2017 - ACS Publications
Alkaline phosphatase (ALP) is an important enzyme but using ALP-instructed self-assembly
of gadolinium nanofibers for enhanced T2-weighted magnetic resonance imaging (MRI) of …

Functionalized magnetic nanoparticles/biopolymer hybrids: synthesis methods, properties and biomedical applications

KR Reddy, PA Reddy, CV Reddy, NP Shetti… - Methods in …, 2019 - Elsevier
Superparamagnetic iron oxide nanoparticles (SPIONs) are the most extensively used
functional nanomaterials as antibacterial agents, and for other biomedical applications due …

Iron (III) contrast agent candidates for MRI: a survey of the structure–effect relationship in the last 15 years of studies

N Kuźnik, M Wyskocka - European Journal of Inorganic …, 2016 - Wiley Online Library
Iron (III) complexes are under investigation as MRI contrast agents, and new challenges
have delineated the way they are being developed. This review article describes the …

Activatable probes for diagnosis and biomarker detection by MRI

M Carril - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
Magnetic resonance imaging (MRI) is a non-invasive imaging technique with widespread
use in diagnosis. Frequently, contrast in MRI is enhanced with the aid of a contrast agent …

Advances in magnetic resonance imaging contrast agents for biomarker detection

S Sinharay, MD Pagel - Annual Review of Analytical Chemistry, 2016 - annualreviews.org
Recent advances in magnetic resonance imaging (MRI) contrast agents have provided new
capabilities for biomarker detection through molecular imaging. MRI contrast agents based …

Supramolecular design based activatable magnetic resonance imaging

WC Geng, Z Zheng, DS Guo - View, 2021 - Wiley Online Library
Magnetic resonance imaging (MRI) has been widely used in clinical diagnosis. In recent
years, activatable MRI probes responding to specific changes in their microenvironment …

The Development of a Smart Magnetic Resonance Imaging and Chemical Exchange Saturation Transfer Contrast Agent for the Imaging of Sulfatase Activity

IM Welleman, F Reeβing, HH Boersma, RAJO Dierckx… - Pharmaceuticals, 2023 - mdpi.com
The molecular imaging of biomarkers plays an increasing role in medical diagnostics. In
particular, the imaging of enzyme activity is a promising approach, as it enables the use of its …

MRI contrast agents in glycobiology

CFGC Geraldes, JA Peters - Molecules, 2022 - mdpi.com
Molecular recognition involving glycoprotein-mediated interactions is ubiquitous in both
normal and pathological natural processes. Therefore, visualization of these interactions …