Molecular strategies for targeting antioxidants to mitochondria: therapeutic implications

N Apostolova, VM Victor - Antioxidants & redox signaling, 2015 - liebertpub.com
Mitochondrial function and specifically its implication in cellular redox/oxidative balance is
fundamental in controlling the life and death of cells, and has been implicated in a wide …

Platelet activation in obesity and metabolic syndrome

F Santilli, N Vazzana, R Liani, MT Guagnano… - Obesity …, 2012 - Wiley Online Library
Obesity is associated with increased cardiovascular disease. Metabolic syndrome (MS)
identifies substantial additional cardiovascular risk beyond the individual risk factors, and is …

Acute impact of tobacco vs electronic cigarette smoking on oxidative stress and vascular function

R Carnevale, S Sciarretta, F Violi, C Nocella, L Loffredo… - Chest, 2016 - Elsevier
Background The vascular safety of electronic cigarettes (e-Cigarettes) must still be clarified.
We compared the impact of e-Cigarettes vs traditional tobacco cigarettes on oxidative stress …

[HTML][HTML] Intake and time dependence of blueberry flavonoid–induced improvements in vascular function: a randomized, controlled, double-blind, crossover …

A Rodriguez-Mateos, C Rendeiro… - The American journal of …, 2013 - Elsevier
Background: There are very limited data regarding the effects of blueberry flavonoid intake
on vascular function in healthy humans. Objectives: We investigated the impact of blueberry …

Atherothrombosis and oxidative stress: mechanisms and management in elderly

F Violi, L Loffredo, R Carnevale… - Antioxidants & redox …, 2017 - liebertpub.com
Significance: The incidence of cardiovascular events (CVEs) increases with age,
representing the main cause of death in an elderly population. Aging is associated with …

Oxidative stress in chronic vascular disease: from prediction to prevention

F Santilli, D D'Ardes, G Davi - Vascular pharmacology, 2015 - Elsevier
This review article is intended to describe the strong relationship between oxidative stress
and vascular disease. Reactive oxygen species (ROS) play an important role in the …

Reactive oxygen species (ROS), intimal thickening, and subclinical atherosclerotic disease

D Burtenshaw, M Kitching, EM Redmond… - Frontiers in …, 2019 - frontiersin.org
Arteriosclerosis causes significant morbidity and mortality worldwide. Central to this process
is the development of subclinical non-atherosclerotic intimal lesions before the appearance …

Immediate antioxidant and antiplatelet effect of atorvastatin via inhibition of Nox2

P Pignatelli, R Carnevale, D Pastori, R Cangemi… - Circulation, 2012 - Am Heart Assoc
Background—Statins exert an antithrombotic effect in patients at risk of or with acute
thrombosis, but no study has investigated whether this effect is immediate and whether there …

Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque

R Carnevale, C Nocella, V Petrozza, V Cammisotto… - Scientific reports, 2018 - nature.com
Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic,
however, its relationship with human atherosclerosis is still to be defined. We investigate if …

Statins as regulators of redox state in the vascular endothelium: beyond lipid lowering

M Margaritis, KM Channon… - Antioxidants & redox …, 2014 - liebertpub.com
Significance: Endothelial dysfunction and the imbalance between nitric oxide (NO) and
reactive oxygen species production in the vascular endothelium are important early steps in …