The crown and the scepter: roles of the protein corona in nanomedicine

R Cai, C Chen - Advanced Materials, 2019 - Wiley Online Library
Engineering nanomaterials are increasingly considered promising and powerful biomedical
tools or devices for imaging, drug delivery, and cancer therapies, but few nanomaterials …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

Polyoxometalate nanomaterials for enhanced reactive oxygen species theranostics

J Liu, M Huang, X Zhang, Z Hua, Z Feng, Y Dong… - Coordination Chemistry …, 2022 - Elsevier
The dual effects of reactive oxygen species (ROS) on living organisms have become a hot
research topic in the biomedical field. Excessive ROS triggers oxidative imbalances in the …

Molecular and supramolecular switches on mesoporous silica nanoparticles

N Song, YW Yang - Chemical Society Reviews, 2015 - pubs.rsc.org
Nanotechnology has attracted much attention because it possesses many advantages to
engineer new organized nanomaterials and endow them with improved performance. In …

The nano-plasma interface: Implications of the protein corona

J Wolfram, Y Yang, J Shen, A Moten, C Chen… - Colloids and Surfaces B …, 2014 - Elsevier
The interactions between nanoparticles and macromolecules in the blood plasma dictate the
biocompatibility and efficacy of nanotherapeutics. Accordingly, the properties of …

In-vitro in-vivo correlation (IVIVC) in nanomedicine: Is protein corona the missing link?

P Jain, RS Pawar, RS Pandey, J Madan, S Pawar… - Biotechnology …, 2017 - Elsevier
One of the unmet challenges in nanotechnology is to understand and establish the
relationship between physicochemical properties of nanoparticles (NPs) and its biological …

Biomolecular corona on nanoparticles: a survey of recent literature and its implications in targeted drug delivery

RM Pearson, VV Juettner, S Hong - Frontiers in chemistry, 2014 - frontiersin.org
Achieving controlled cellular responses of nanoparticles (NP) is critical for the successful
development and translation of NP-based drug delivery systems. However, precise control …

Impact of protein corona on the biological identity of nanomedicine: understanding the fate of nanomaterials in the biological milieu

MH Akhter, H Khalilullah, M Gupta, MA Alfaleh… - Biomedicines, 2021 - mdpi.com
Nanoparticles (NPs) in contact with a biological medium are rapidly comprehended by a
number of protein molecules resulting in the formation of an NP–protein complex called …

A health concern regarding the protein corona, aggregation and disaggregation

M Falahati, F Attar, M Sharifi, T Haertlé, JF Berret… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Nanoparticle (NP)–protein complexes exhibit the “correct identity” of NP in biological media.
Therefore, protein–NP interactions should be closely explored to understand and modulate …