IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
K Taniguchi, M Karin - Seminars in immunology, 2014 - Elsevier
Inflammatory responses play pivotal roles in cancer development, including tumor initiation,
promotion, progression, and metastasis. Cytokines are now recognized as important …
promotion, progression, and metastasis. Cytokines are now recognized as important …
Telomerase: central regulator of all of the hallmarks of cancer
KC Low, V Tergaonkar - Trends in biochemical sciences, 2013 - cell.com
The hallmarks of cancer described by Hanahan and Weinberg are properties that cancer
cells must possess for successful transformation. It is believed that each of these hallmarks …
cells must possess for successful transformation. It is believed that each of these hallmarks …
MicroRNA-based therapy and breast cancer: A comprehensive review of novel therapeutic strategies from diagnosis to treatment
Abstract MicroRNAs (miRNA) are 21–23 nucleotide molecules not translated into proteins
that bind and target the 3′ untranslated regions of mRNA. These characteristics make them …
that bind and target the 3′ untranslated regions of mRNA. These characteristics make them …
[PDF][PDF] In vivo and in vitro impact of miR-31 and miR-143 on the suppression of metastasis and invasion in breast cancer
S Soheilyfar, Z Velashjerdi, YS Hajizadeh, NF Maroufi… - J buon, 2018 - researchgate.net
Summary Purpose: The microRNA (miR)-31 and miR-143 are pleiotropic anti-metastatic
miRs, with an expression that decreases significantly in metastatic breast cancer cells. The …
miRs, with an expression that decreases significantly in metastatic breast cancer cells. The …
Differentially expressed miRNAs in ulcerative colitis and Crohn's disease
R Yarani, A Shojaeian, O Palasca… - Frontiers in …, 2022 - frontiersin.org
Differential microRNA (miRNA or miR) regulation is linked to the development and progress
of many diseases, including inflammatory bowel disease (IBD). It is well-established that …
of many diseases, including inflammatory bowel disease (IBD). It is well-established that …
The emerging role of miRNAs in inflammatory bowel disease: a review
CG Chapman, J Pekow - Therapeutic advances in …, 2015 - journals.sagepub.com
Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, is
believed to develop as a result of a deregulated inflammatory response to environmental …
believed to develop as a result of a deregulated inflammatory response to environmental …
SOCS3 as a future target to treat metabolic disorders
JAB Pedroso, AM Ramos-Lobo, J Donato - Hormones, 2019 - Springer
The suppressors of cytokine signaling (SOCS) are a group of eight proteins responsible for
preventing excessive cytokine signaling. Among this protein family, SOCS3 has received …
preventing excessive cytokine signaling. Among this protein family, SOCS3 has received …
[HTML][HTML] MicroRNA as tools and therapeutics in lung cancer
JF Barger, SP Nana-Sinkam - Respiratory medicine, 2015 - Elsevier
Lung cancer is the number one cause of cancer related deaths. The lack of specific and
accurate tools for early diagnosis and minimal targeted therapeutics both contribute to poor …
accurate tools for early diagnosis and minimal targeted therapeutics both contribute to poor …
Interplay between microRNAs and the STAT3 signaling pathway in human cancers
Q Cao, YY Li, WF He, ZZ Zhang, Q Zhou… - Physiological …, 2013 - journals.physiology.org
MicroRNAs (miRNAs, also miR) are a class of noncoding endogenous RNAs that regulate
gene expression through binding to protein-coding messenger RNA (mRNA) molecules …
gene expression through binding to protein-coding messenger RNA (mRNA) molecules …
The mystery of let-7d–a small RNA with great power
T Kolenda, W Przybyła, A Teresiak… - Contemporary …, 2014 - termedia.pl
miRNAs belong to a class of small non-coding RNAs which can modulate gene expression.
Disturbances in their expression and function may cause cancer formation, progression and …
Disturbances in their expression and function may cause cancer formation, progression and …