Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central
and peripheral nervous systems and with diverse roles in multiple physiological processes …

Neuropeptide Y (NPY) is a sympathetic neurotransmitter with pleiotropic actions, many of
which are highly relevant to tumor biology. Consequently, the peptide has been implicated …

Adverse prognosis in Ewing sarcoma (ES) is associated with the presence of metastases,
particularly in bone, tumor hypoxia and chromosomal instability (CIN). Yet, a mechanistic …

Aims The co-transmitter neuropeptide-Y (NPY) is released during high sympathetic drive,
including ST-elevation myocardial infarction (STEMI), and can be a potent vasoconstrictor …

In diabetic cardiomyopathy, there is altered angiogenic signaling and increased oxidative
stress. As a result, anti-angiogenic and pro-inflammatory pathways are activated. These …

Neuropeptides are emerging as key regulators of stem cell niche activities in health and
disease, both inside and outside the central nervous system (CNS). Among them …

BACKGROUND Prior studies have suggested an association between platelet transfusions
(PTXs) and worse outcomes among infants with necrotizing enterocolitis (NEC), potentially …

Neuropeptide Y (NPY), a powerful neurotransmitter of the central nervous system, is a key
regulator of angiogenesis and biology of adipose depots. Intriguingly, its peripheral vascular …

Ewing sarcoma (ES) is an aggressive malignancy driven by an oncogenic fusion protein,
EWS-FLI1. Neuropeptide Y (NPY), and two of its receptors, Y1R and Y5R are up-regulated …

Neuropeptide Y (NPY) is a multifunctional neurotransmitter acting via G protein-coupled
receptors-Y1R, Y2R and Y5R. NPY activities, such as its proliferative effects, are mediated …