The association of multiple interacting genes with specific phenotypes in rice using gene coexpression networks

SP Ficklin, F Luo, FA Feltus - Plant physiology, 2010 - academic.oup.com
Discovering gene sets underlying the expression of a given phenotype is of great
importance, as many phenotypes are the result of complex gene-gene interactions. Gene …

Weighted general group lasso for gene selection in cancer classification

Y Wang, X Li, R Ruiz - IEEE transactions on cybernetics, 2018 - ieeexplore.ieee.org
Relevant gene selection is crucial for analyzing cancer gene expression datasets including
two types of tumors in cancer classification. Intrinsic interactions among selected genes …

Grouped gene selection of cancer via adaptive sparse group lasso based on conditional mutual information

J Li, W Dong, D Meng - IEEE/ACM transactions on …, 2017 - ieeexplore.ieee.org
This paper deals with the problems of cancer classification and grouped gene selection. The
weighted gene co-expression network on cancer microarray data is employed to identify …

Weighted frequent gene co-expression network mining to identify genes involved in genome stability

J Zhang, K Lu, Y Xiang, M Islam, S Kotian, Z Kais… - 2012 - journals.plos.org
Gene co-expression network analysis is an effective method for predicting gene functions
and disease biomarkers. However, few studies have systematically identified co-expressed …

Connectivity in gene coexpression networks negatively correlates with rates of molecular evolution in flowering plants

RR Masalia, AJ Bewick, JM Burke - PLoS One, 2017 - journals.plos.org
Gene coexpression networks are a useful tool for summarizing transcriptomic data and
providing insight into patterns of gene regulation in a variety of species. Though there has …

Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease

AJ Levine, JA Miller, P Shapshak, B Gelman… - BMC medical …, 2013 - Springer
Abstract Background Human Immunodeficiency Virus-1 (HIV) infection frequently results in
neurocognitive impairment. While the cause remains unclear, recent gene expression …

Massive-scale gene co-expression network construction and robustness testing using random matrix theory

SM Gibson, SP Ficklin, S Isaacson, F Luo, FA Feltus… - PloS one, 2013 - journals.plos.org
The study of gene relationships and their effect on biological function and phenotype is a
focal point in systems biology. Gene co-expression networks built using microarray …

A new model to study neurodegeneration in ataxia oculomotor apraxia type 2

OJ Becherel, J Sun, AJ Yeo, S Nayler… - Human Molecular …, 2015 - academic.oup.com
Ataxia oculomotor apraxia type 2 (AOA2) is a rare autosomal recessive cerebellar ataxia.
Recent evidence suggests that the protein defective in this syndrome, senataxin (SETX) …

Normalized imqcm: An algorithm for detecting weak quasi-cliques in weighted graph with applications in gene co-expression module discovery in cancers

J Zhang, K Huang - Cancer informatics, 2014 - journals.sagepub.com
In this paper, we present a new approach for mining weighted networks to identify densely
connected modules such as quasi-cliques. Quasi-cliques are densely connected …

Identification of prognostic markers of high grade prostate cancer through an integrated bioinformatics approach

H Huang, Q Zhang, C Ye, JM Lv, X Liu, L Chen… - Journal of Cancer …, 2017 - Springer
Purpose Prostate cancer is one of the leading causes of cancer death for male. In the
present study, we applied an integrated bioinformatics approach to provide a novel …