The gut has been hypothesized to be the motor of multiple organ dysfunction syndrome
(MODS) for the past quarter century. 1–3 Whereas initial theories of gut and critical illness …

Background Gastrointestinal (GI) dysfunction is frequent in the critically ill but can be
overlooked as a result of the lack of standardization of the diagnostic and therapeutic …

Background & aims To develop a five grade score (0–4 points) for the assessment of
gastrointestinal (GI) dysfunction in adult critically ill patients. Methods This prospective …

Background & aims Intestinal failure (IF) is defined as “the reduction of gut function below
the minimum necessary for the absorption of macronutrients and/or water and electrolytes …

Enteral feeding intolerance (EFI) is a common feature in critically ill patients worldwide.
However, there is no clear, widely agreed‐upon definition available, with various studies …

Introduction To determine the nutrition practice in intensive care units and the associated
outcome across the world, a yearly 1 day cross sectional audit was performed from 2007 to …

Clinicians and researchers frequently use the phrase 'feeding intolerance'(FI) as a
descriptive term in enterally fed critically ill patients. We aimed to:(1) determine what is the …

The gastrointestinal tract has long been hypothesized to function as “the motor” of multiple
organ dysfunction syndrome. The gastrointestinal microenvironment is comprised of a single …

All components of the gut are adversely impacted by critical illness. Gut injury can not only
propagate local damage, but can also cause distant injury and organ failure. Understanding …

Failure of gut homeostasis is an important factor in the pathogenesis and progression of
systemic inflammation, which can culminate in multiple organ failure and fatality. Pathogenic …