[HTML][HTML] Gut microbiome in gastrointestinal cancer: a friend or foe?

Y Liu, Y Baba, T Ishimoto, X Gu, J Zhang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The impact of the gut microbiome on host health is becoming increasingly recognized. To
date, there is growing evidence that the complex characteristics of the microbial community …

Understanding the mechanisms and translational implications of the microbiome for cancer therapy innovation

J Queen, F Shaikh, CL Sears - Nature Cancer, 2023 - nature.com
The intersection of the microbiota and cancer and the mechanisms that define these
interactions are a fascinating, rapidly evolving area of cancer biology and therapeutics. Here …

Helicobacter pylori, Homologous-Recombination Genes, and Gastric Cancer

Y Usui, Y Taniyama, M Endo… - … England Journal of …, 2023 - Mass Medical Soc
Background Helicobacter pylori infection is a well-known risk factor for gastric cancer.
However, the contribution of germline pathogenic variants in cancer-predisposing genes …

Helicobacter pylori infection: a dynamic process from diagnosis to treatment

Q Sun, C Yuan, S Zhou, J Lu, M Zeng, X Cai… - Frontiers in cellular and …, 2023 - frontiersin.org
Helicobacter pylori, a gram-negative microaerophilic pathogen, causes several upper
gastrointestinal diseases, such as chronic gastritis, peptic ulcer disease, and gastric cancer …

Helicobacter pylori and the Role of Lipopolysaccharide Variation in Innate Immune Evasion

D Sijmons, AJ Guy, AK Walduck… - Frontiers in …, 2022 - frontiersin.org
Helicobacter pylori is an important human pathogen that infects half the human population
and can lead to significant clinical outcomes such as acute and chronic gastritis, duodenal …

The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells

A Takahashi-Kanemitsu, M Lu, CT Knight… - Science …, 2023 - science.org
Helicobacter pylori strains that deliver the oncoprotein CagA into gastric epithelial cells are
the major etiologic agents of upper gastric diseases including gastric cancer. CagA …

An Overview of Helicobacter pylori Survival Tactics in the Hostile Human Stomach Environment

YY Cheok, CYQ Lee, HC Cheong, J Vadivelu, CY Looi… - Microorganisms, 2021 - mdpi.com
Helicobacter pylori is well established as a causative agent for gastritis, peptic ulcer, and
gastric cancer. Armed with various inimitable virulence factors, this Gram-negative bacterium …

The conundrum of Helicobacter pylori-associated apoptosis in gastric cancer

MCC Lim, P Jantaree, M Naumann - Trends in Cancer, 2023 - cell.com
Helicobacter pylori is a human microbial pathogen that colonizes the gastric epithelium and
causes type B gastritis with varying degrees of active inflammatory infiltrates. The underlying …

The cross talk between gastric cancer stem cells and the immune microenvironment: a tumor-promoting factor

J Becerril-Rico, E Alvarado-Ortiz… - Stem Cell Research & …, 2021 - Springer
Cross talk between cancer cells and the immune system is determinant for cancer
progression. Emerging evidence demonstrates that GC characteristics such as metastasis …

Oral-intestinal microbiota in colorectal cancer: inflammation and immunosuppression

S Mo, H Ru, M Huang, L Cheng, X Mo… - Journal of Inflammation …, 2022 - Taylor & Francis
It is widely recognized that microbial disorders are involved in the pathogenesis of many
malignant tumors. The oral and intestinal tract are two of the overriding microbial habitats in …