Terpene synthases as metabolic gatekeepers in the evolution of plant terpenoid chemical diversity
PS Karunanithi, P Zerbe - Frontiers in plant science, 2019 - frontiersin.org
Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …
distributed across all domains of life. Plants produce by far the largest array of terpenoids …
Terpenoid synthase structures: a so far incomplete view of complex catalysis
Covering: up to February 2012 The complexity of terpenoid natural products has drawn
significant interest, particularly since their common (poly) isoprenyl origins were discovered …
significant interest, particularly since their common (poly) isoprenyl origins were discovered …
Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins
A long‐standing goal in plant research is to optimize the protective function of biochemical
agents that impede pest and pathogen attack. Nearly 40 years ago, pathogen‐inducible …
agents that impede pest and pathogen attack. Nearly 40 years ago, pathogen‐inducible …
To gibberellins and beyond! Surveying the evolution of (di) terpenoid metabolism
The diterpenoids are classically defined by their composition—four isoprenyl units (20
carbons)—and are generally derived from [E, E, E]-geranylgeranyl diphosphate (GGPP) …
carbons)—and are generally derived from [E, E, E]-geranylgeranyl diphosphate (GGPP) …
Plant diterpene synthases: exploring modularity and metabolic diversity for bioengineering
P Zerbe, J Bohlmann - Trends in biotechnology, 2015 - cell.com
Plants produce thousands of diterpenoid natural products; some of which are of significant
industrial value as biobased pharmaceuticals (taxol), fragrances (sclareol), food additives …
industrial value as biobased pharmaceuticals (taxol), fragrances (sclareol), food additives …
Genetic evidence for natural product‐mediated plant–plant allelopathy in rice (Oryza sativa)
There is controversy as to whether specific natural products play a role in directly mediating
antagonistic plant–plant interactions–that is, allelopathy. If proved to exist, such phenomena …
antagonistic plant–plant interactions–that is, allelopathy. If proved to exist, such phenomena …
Plant (di) terpenoid evolution: from pigments to hormones and beyond
Z Wang, DR Nelson, J Zhang, X Wan… - Natural product reports, 2023 - pubs.rsc.org
Covering: up to 2014–2022. Diterpenoid biosynthesis in plants builds on the necessary
production of (E, E, E)-geranylgeranyl diphosphate (GGPP) for photosynthetic pigment …
production of (E, E, E)-geranylgeranyl diphosphate (GGPP) for photosynthetic pigment …
Discovery, biosynthesis and stress-related accumulation of dolabradiene-derived defenses in maize
Terpenoids are a major component of maize (Zea mays) chemical defenses that mediate
responses to herbivores, pathogens, and other environmental challenges. Here, we …
responses to herbivores, pathogens, and other environmental challenges. Here, we …
Manoyl Oxide (13R), the Biosynthetic Precursor of Forskolin, Is Synthesized in Specialized Root Cork Cells in Coleus forskohlii
I Pateraki, J Andersen-Ranberg, B Hamberger… - Plant …, 2014 - academic.oup.com
Forskolin, a complex labdane diterpenoid found in the root of Coleus forskohlii (Lamiaceae),
has received attention for its broad range of pharmacological activities, yet the biosynthesis …
has received attention for its broad range of pharmacological activities, yet the biosynthesis …
Multiple genes recruited from hormone pathways partition maize diterpenoid defences
Duplication and divergence of primary pathway genes underlie the evolution of plant
specialized metabolism; however, mechanisms partitioning parallel hormone and defence …
specialized metabolism; however, mechanisms partitioning parallel hormone and defence …