Cell based advanced therapeutic medicinal products for bone repair: Keep it simple?
The development of cell based advanced therapeutic medicinal products (ATMPs) for bone
repair has been expected to revolutionize the health care system for the clinical treatment of …
repair has been expected to revolutionize the health care system for the clinical treatment of …
Construction of a bilayered vascular graft with smooth internal surface for improved hemocompatibility and endothelial cell monolayer formation
Formation of a continuous endothelial cell (EC) monolayer inside the luminal surface with
enhanced hemocompatibility, is a promising solution for improving performance and overall …
enhanced hemocompatibility, is a promising solution for improving performance and overall …
Modeling large-volume subcutaneous injection of monoclonal antibodies with anisotropic porohyperelastic models and data-driven tissue layer geometries
Subcutaneous injection of therapeutic monoclonal antibodies (mAbs) has become one of
the fastest-growing fields in the pharmaceutical industry. The transport and mechanical …
the fastest-growing fields in the pharmaceutical industry. The transport and mechanical …
Computational modeling of the effect of skin pinch and stretch on subcutaneous injection of monoclonal antibodies using autoinjector devices
Subcutaneous injection of monoclonal antibodies (mAbs) has experienced unprecedented
growth in the pharmaceutical industry due to its benefits in patient compliance and cost …
growth in the pharmaceutical industry due to its benefits in patient compliance and cost …
Optimization and validation of a custom-designed perfusion bioreactor for bone tissue engineering: Flow assessment and optimal culture environmental conditions
S Yamada, MA Yassin, T Schwarz, K Mustafa… - … in Bioengineering and …, 2022 - frontiersin.org
Various perfusion bioreactor systems have been designed to improve cell culture with three-
dimensional porous scaffolds, and there is some evidence that fluid force improves the …
dimensional porous scaffolds, and there is some evidence that fluid force improves the …
Transport and distribution of biotherapeutics in different tissue layers after subcutaneous injection
The subcutaneous injection is the main route of administration for monoclonal antibodies
(mAbs) and several other biotherapeutics due to the patient comfort and cost-effectiveness …
(mAbs) and several other biotherapeutics due to the patient comfort and cost-effectiveness …
Transport and lymphatic uptake of monoclonal antibodies after subcutaneous injection
The subcutaneous injection has emerged to become a feasible self-administration practice
for biotherapeutics due to the patient comfort and cost-effectiveness. However, the available …
for biotherapeutics due to the patient comfort and cost-effectiveness. However, the available …
A facile method to determine pore size distribution in porous scaffold by using image processing
Image processing permits scientists to investigate morphological properties of three-
dimensional structures starting from their bi-dimensional gray-scale representation. In many …
dimensional structures starting from their bi-dimensional gray-scale representation. In many …
Modeling drug transport and absorption in subcutaneous injection of monoclonal antibodies: Impact of tissue deformation, devices, and physiology
The pharmaceutical industry has experienced a remarkable increase in the use of
subcutaneous injection of monoclonal antibodies (mAbs), attributed mainly to its advantages …
subcutaneous injection of monoclonal antibodies (mAbs), attributed mainly to its advantages …
Regenerative orthopaedics: in vitro, in vivo… in silico
L Geris - International orthopaedics, 2014 - Springer
In silico, defined in analogy to in vitro and in vivo as those studies that are performed on a
computer, is an essential step in problem-solving and product development in classical …
computer, is an essential step in problem-solving and product development in classical …