Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Diabetic neuropathy is a neurological complication of diabetes that causes significant
morbidity and, because of the obesity-driven rise in incidence of type 2 diabetes, is …

Diabetic neuropathy is a major complication of diabetes that affects the sensory and
autonomic nervous systems and leads to significant morbidity and impact on the quality of …

Poly (ADP-ribose) polymerase (PARP) activation is emerging as a fundamental mechanism
in the pathogenesis of diabetes complications including diabetic neuropathy. This study …

OBJECTIVE—Axonal regeneration is defective in both experimental and clinical diabetic
neuropathy, contributing to loss of axonal extremities and neuronal dysfunction. The …

In this article we describe differences in early metabolic abnormalities between type 1 and
type 2 diabetic polyneuropathy (DPN), and how these differences lead to milder initial …

Diabetic peripheral neuropathy (DPN) is the most common complication in both type 1 and
type 2 diabetes. Here we studied some phenotypic features of a well-established animal …

Diabetic polyneuropathy (DPN) is a common but intractable degenerative disorder of
peripheral neurons. DPN first results in retraction and loss of sensory terminals in target …

Aims/hypothesis The aim of this study was to evaluate the nature and extent of neuronal loss
in dorsal root ganglia (DRG) in diabetic polyneuropathy. Materials and methods We …

We investigated the polyol pathway activity and the gene expression profiles in immortalized
adult mouse Schwann cells (IMS32) under normal (5.6 mm) and high (30 and 56 mm) …