Annual research review: Early adversity, the hypothalamic–pituitary–adrenocortical axis, and child psychopathology
Background Research on early adversity, stress biology, and child development has grown
exponentially in recent years. Findings We review the current evidence for the hypothalamic …
exponentially in recent years. Findings We review the current evidence for the hypothalamic …
Cortisol and major depressive disorder—translating findings from humans to animal models and back
Major depressive disorder (MDD) is a global problem for which current pharmacotherapies
are not completely effective. Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has …
are not completely effective. Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has …
Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …
nervous-system development, health, and behavior is critically important for developing …
[图书][B] Multisystemic resilience: Adaptation and transformation in contexts of change
M Ungar - 2021 - books.google.com
" Across diverse disciplines, the term resilience is appearing more and more often. However,
while each discipline has developed theory and models to explain the resilience of the …
while each discipline has developed theory and models to explain the resilience of the …
Preventing childhood toxic stress: partnering with families and communities to promote relational health
A Garner, M Yogman - Pediatrics, 2021 - publications.aap.org
By focusing on the safe, stable, and nurturing relationships (SSNRs) that buffer adversity
and build resilience, pediatric care is on the cusp of a paradigm shift that could reprioritize …
and build resilience, pediatric care is on the cusp of a paradigm shift that could reprioritize …
Methods to assess adverse childhood experiences of children and families: Toward approaches to promote child well-being in policy and practice
CD Bethell, A Carle, J Hudziak, N Gombojav… - Academic pediatrics, 2017 - Elsevier
Background Advances in human development sciences point to tremendous possibilities to
promote healthy child development and well-being across life by proactively supporting …
promote healthy child development and well-being across life by proactively supporting …
Effects of the social environment and stress on glucocorticoid receptor gene methylation: a systematic review
The early-life social environment can induce stable changes that influence
neurodevelopment and mental health. Research focused on early-life adversity revealed …
neurodevelopment and mental health. Research focused on early-life adversity revealed …
The role of early growth response 1 (EGR1) in brain plasticity and neuropsychiatric disorders
F Duclot, M Kabbaj - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
It is now clearly established that complex interactions between genes and environment are
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …
A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches
Childhood maltreatment is a major risk factor for chronic and severe mental and physical
health problems across the lifespan. Increasing evidence supports the hypothesis that …
health problems across the lifespan. Increasing evidence supports the hypothesis that …
[HTML][HTML] Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress-related disorders causality: a critical review
Early life stress (ELS) is a known risk factor for suffering psychopathology in adulthood. The
hypothalamic–pituitary–adrenal (HPA) axis has been described to be deregulated in both …
hypothalamic–pituitary–adrenal (HPA) axis has been described to be deregulated in both …