There is a consensus that the antifungal repertoire for the treatment of cryptococcal
infections is limited. Standard treatment involves the administration of an antifungal drug …

Cryptococcosis is a global fungal infection caused by the Cryptococcus neoformans/
Cryptococcus gattii yeast complex. This infection is acquired by inhalation of propagules …

Propolis is a natural substance and consists of bioactive compounds, which gives it
antioxidant and antimicrobial properties. However, the use of propolis is limited by the low …

Fungi have traditionally been considered opportunistic pathogens in primary infections
caused by virulent bacteria, protozoan, or viruses. Consequently, antimycotic chemotherapy …

Secretory phospholipase B1 (PLB1) and biofilms act as microbial virulence factors and play
an important role in pulmonary cryptococcosis. This study aims to formulate the ethanolic …

Ethnopharmacological relevance Paracoccidioidomycosis (PCM) is a systemic mycosis with
high prevalence in South America and especially in Brazil with severe clinical …

Chromoblastomycosis (CBM) is a neglected human implantation mycosis caused by several
dematiaceous fungal species. Currently available therapy is usually associated with …

In this study, we describe a nano-carrier system for propolis that is able to cross an in vitro
model of the blood-brain barrier (BBB) and effectively reduce the virulence of Cryptococcus …

Stingless bees, also known as meliponines, live in beehives. However, reports on the
distribution of stingless bees are scattered, resulting in a lack of precision. Honey and …

Cryptococcus neoformans, a life-threatening human yeast pathogen, has the ability to
produce melanin, which is one of the common virulence factors contributing to cryptococcal …