Although the biological functions of cell and tissue can be regulated by biochemical factors
(eg, growth factors, hormones), the biophysical effects of materials on the regulation of …

Myocardial infarction (MI) has been considered as the leading cause of cardiovascular-
related deaths worldwide. Although traditional therapeutic agents including various …

In the past few years, a considerable amount of effort has been devoted toward the
development of biomimetic scaffolds for cardiac tissue engineering. However, most of the …

Stem cells are the future in tissue engineering and regeneration. In a co‐culture, stem cells
not only provide a target cell source with multipotent differentiation capacity, but can also act …

A bioengineered construct that matches the chemical, mechanical, biological properties and
extracellular matrix morphology of native tissue could be suitable as a cardiac patch for …

It is estimated that by 2030, almost 23.6 million people will perish from cardiovascular
disease, according to the WHO. The review discusses advances in stem cell therapy for …

In order to translate preclinical data into the clinical studies, relevant in vitro models with
structure and key functional properties similar to native human tissue should be used. In vitro …

In an effort to reduce organ replacement and enhance tissue repair, there has been a
tremendous effort to create biomechanically optimized scaffolds for tissue engineering …

The influence of somatic stem cells in the stimulation of mammalian cardiac muscle
regeneration is still in its early stages, and so far, it has been difficult to determine the …

The healthy heart comprises many different cell types that work together to preserve optimal
function. However, in a diseased heart the function of one or more cell types is compromised …