An open-label phase I/IIa clinical trial of 11β-HSD1 inhibitor for cushing's syndrome and autonomous cortisol secretion

S Oda, K Ashida, M Uchiyama… - The Journal of …, 2021 - academic.oup.com
Context 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors demonstrate
antimetabolic and antisarcopenic effects in Cushing's syndrome (CS) and autonomous …

Hydrocortisone‐Containing Animal‐Derived Food Intake Affects Lipid Nutrients Utilization

W Jia, X Wu, L Shi - Molecular Nutrition & Food Research, 2022 - Wiley Online Library
Scope As the tremendous increases in consumption of animal‐derived food, endogenous
hydrocortisone migrating along the food chain to organism arouses extensive attention. This …

Serum levels of n-3 and n-6 polyunsaturated fatty acids in patients with systemic lupus erythematosus and their association with disease activity: a pilot study

D Gorczyca, B Szponar, M Paściak… - Scandinavian Journal …, 2022 - Taylor & Francis
Objective Polyunsaturated fatty acids (PUFAs) may modulate the inflammatory process in
systemic autoimmune diseases, including systemic lupus erythematosus (SLE). The aim of …

Time Course of Metabolic Alterations Associated with the Progression of Systemic Lupus Erythematosus in MRL/lpr Mice Based on GC/MS

J Liu, D Zhang, K Wang, Z Li, Z He, D Wu… - Journal of Proteome …, 2020 - ACS Publications
Exploring the dynamic changes of metabolites and metabolic pathways during the
development of the disease can help to further understand the etiology and pathogenesis of …

[HTML][HTML] The influence of dexamethasone on hepatic fatty acids metabolism and transport in human steatotic HepG2 cell line exposed to palmitate

K Sztolsztener, E Harasim-Symbor… - Biochemical and …, 2021 - Elsevier
Dexamethasone (DEX) is a synthetic glucocorticoid with anti-inflammatory properties. We
evaluated a potentially protective dexamethasone influence on hepatocellular lipid …

Tools and approaches for assessing stress-responsive secondary metabolites to design climate-smart crops

DR Das, M Sarkar, A Paul - Biology and Biotechnology of …, 2023 - taylorfrancis.com
Agricultural environments are constantly jeopardized by abiotic stresses, including
periodical droughts, temperature extremes, water deficit, flooding, salinity, and changes in …

Terpenoid Production Through Mevalonate and Methylerythritol Phosphate Pathway and Regulation of Environmental Stress Tolerance

L Sathee, MK Malini, P Kumar… - … and Biotechnology of …, 2023 - taylorfrancis.com
Two spatially separated yet inter-connected pathways, mevalonic acid (MVA) and
methylerythritol phosphate (MEP) pathways generate terpenoid precursors in plants …

Relationship of the Inflammatory Diet Status and Dietary Intake with Antimalarial Treatment in Systemic Lupus Rrythematosus: A Cross-Sectional Study

MR Meza-Meza, N Shivappa, M Montoya-Buelna… - 2020 - researchsquare.com
Background: Systemic lupus erythematosus (SLE) is the prototype autoimmune disease with
high inflammatory cytokine levels. In autoimmune conditions, diet could modify the …