Curcumin enhances elvitegravir concentration and alleviates oxidative stress and inflammatory response
In this study, we investigated the potential of using curcumin (CUR) as an adjuvant to
enhance the delivery of antiretroviral drug elvitegravir (EVG) across the BBB, and alleviate …
enhance the delivery of antiretroviral drug elvitegravir (EVG) across the BBB, and alleviate …
LM11A-31, a modulator of p75 neurotrophin receptor, suppresses HIV-1 replication and inflammatory response in macrophages
G Mirzahosseini, N Sinha, L Zhou… - Experimental …, 2024 - pmc.ncbi.nlm.nih.gov
Antiretroviral drugs have made significant progress in treating HIV-1 and improving the
quality of HIV-1-infected individuals. However, due to their limited permeability into the brain …
quality of HIV-1-infected individuals. However, due to their limited permeability into the brain …
Darunavir Nanoformulation Suppresses HIV Pathogenesis in Macrophages and Improves Drug Delivery to the Brain in Mice
Although antiretroviral therapy (ART) can suppress peripheral HIV, patients still suffer from
neuroHIV due to insufficient levels of ART drugs in the brain. Hence, this study focuses on …
neuroHIV due to insufficient levels of ART drugs in the brain. Hence, this study focuses on …
Resveratrol and its analogs suppress HIV replication, oxidative stress, and inflammation in macrophages
Objectives HIV suppression in brain viral reservoirs, especially macrophages, and microglia
is critical to suppress HIV neuropathogenesis and subsequently HIV-associated …
is critical to suppress HIV neuropathogenesis and subsequently HIV-associated …
Extracellular Vesicles Secreted by the Activated THP-1 Cells Influence the Inflammation Gene Expression in Zebrafish
DB Sambur, OV Kalinina, AD Aquino, PV Tirikova… - Neurochemical …, 2024 - Springer
Extracellular vesicles secreted by immune cells may play a significant role in the initiation,
maintenance, and progression of systemic inflammation. The aim of the study was to …
maintenance, and progression of systemic inflammation. The aim of the study was to …
Extracellular vesicles secreted by the ТНР-1 cells influence on the inflammation gene expression in zebrafish
DB Sambur, OV Kalinina, AD Aquino, PV Tirikova… - …, 2024 - journals.rcsi.science
Extracellular vesicles secreted by immune cells may play a significant role in the initiation,
maintenance, and progression of systemic inflammation. The aim of the study was to …
maintenance, and progression of systemic inflammation. The aim of the study was to …