Measuring DNA modifications with the comet assay: a compendium of protocols

A Collins, P Møller, G Gajski, S Vodenková… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …

Ecotoxicological applications and significance of the comet assay

AN Jha - Mutagenesis, 2008 - academic.oup.com
Application of the single-cell gel electrophoresis or comet assay has revolutionized the field
of genetic ecotoxicology or eco-genotoxicology. It is a rapid, sensitive and relatively …

Comet assay: a reliable tool for the assessment of DNA damage in different models

A Dhawan, M Bajpayee, D Parmar - Cell biology and toxicology, 2009 - Springer
New chemicals are being added each year to the existing burden of toxic substances in the
environment. This has led to increased pollution of ecosystems as well as deterioration of …

Cypermethrin has the potential to induce hepatic oxidative stress, DNA damage and apoptosis in adult zebrafish (Danio rerio)

Y Jin, S Zheng, Y Pu, L Shu, L Sun, W Liu, Z Fu - Chemosphere, 2011 - Elsevier
Cypermethrin (CYP), a widely used Type II pyrethroid pesticide, is one of the most common
contaminants in the freshwater aquatic system. We studied the effects of CYP exposure on …

Protective effect of the newly synthesized and characterized charge transfer (CT) complex against arecoline induced toxicity in third-instar larvae of transgenic …

S Shakya, IM Khan, B Shakya, YH Siddique… - Journal of Materials …, 2023 - pubs.rsc.org
Agents that suppress the toxic effect of arecoline (a chemical present in the Areca nut fruit)
have become a need of the hour owing to its several harmful effects on human beings …

Evaluation of basil extract (Ocimum basilicum L.) on oxidative, anti-genotoxic and anti-inflammatory effects in human leukocytes cell cultures exposed to challenging …

CM Güez, RO Souza, P Fischer, MFM Leão… - Brazilian Journal of …, 2017 - SciELO Brasil
Ocimum is one of the most important genera of the Lamiaceae family. Several studies about
basil and its popular use reveal many characteristics of the herb, including its use as …

Lead (Pb) induced oxidative stress as a mechanism to cause neurotoxicity in Drosophila melanogaster

O Shilpa, KP Anupama, A Antony, HP Gurushankara - Toxicology, 2021 - Elsevier
The widespread use of lead (Pb) has caused global contamination, inevitable human
exposure, and public health problems. Pb neurotoxicity has been linked to various human …

Interactions of ingested polystyrene microplastics with heavy metals (cadmium or silver) as environmental pollutants: a comprehensive in vivo study using Drosophila …

F Turna Demir, G Akkoyunlu, E Demir - Biology, 2022 - mdpi.com
Simple Summary Living organisms are now constantly exposed to PSMPLs, and besides
their huge toxic potential, they can also act as carriers of various hazardous elements such …

Cypermethrin-induced DNA damage in organs and tissues of the mouse: evidence from the comet assay

S Patel, AK Pandey, M Bajpayee, D Parmar… - … /Genetic Toxicology and …, 2006 - Elsevier
Cypermethrin is the most widely used Type II pyrethroid pesticide because of its high
effectiveness against target species and its low mammalian toxicity reported so far. It is a fast …

Biosynthesis and Characterization of Extracellular Silver Nanoparticles from Streptomyces aizuneusis: Antimicrobial, Anti Larval, and Anticancer Activities

HM Abd-Elhady, MA Ashor, A Hazem, FM Saleh… - Molecules, 2021 - mdpi.com
The ability of microorganisms to reduce inorganic metals has launched an exciting eco-
friendly approach towards developing green nanotechnology. Thus, the synthesis of metal …