Oxamic acids: useful precursors of carbamoyl radicals

IM Ogbu, G Kurtay, F Robert, Y Landais - Chemical Communications, 2022 - pubs.rsc.org
This review article describes the recent development in the chemistry of carbamoyl radicals
generated from oxamic acids. This mild and efficient method compares well with previous …

Organoelectrophotocatalytic Generation of Acyl Radicals from Formamides and Aldehydes: Access to Acylated 3-CF3-2-Oxindoles

H He, Q Wan, ZW Hou, Q Zhou, L Wang - Organic Letters, 2023 - ACS Publications
Organoelectrophotocatalytic generation of acyl radicals from formamides and aldehydes to
synthesize acylated 3-CF3-2-oxindoles has been developed. This protocol features a …

Photoinduced carbamoylation reactions: unlocking new reactivities towards amide synthesis

BT Matsuo, PHR Oliveira, EF Pissinati… - Chemical …, 2022 - pubs.rsc.org
The preparation of amide-containing compounds is among the most interesting and
challenging topics for the synthetic community. Such relevance is given by their reactive …

Site-selective C–O bond editing of unprotected saccharides

G Wang, CC Ho, Z Zhou, YJ Hao, J Lv… - Journal of the …, 2023 - ACS Publications
Glucose and its polyhydroxy saccharide analogs are complex molecules that serve as
essential structural components in biomacromolecules, natural products, medicines, and …

The cost of quantum yield

JR Swierk - Organic Process Research & Development, 2023 - ACS Publications
The quantum yield (QY) of a photocatalytic reaction significantly influences its performance,
as reactions with low QYs require more intense light sources and longer illumination times to …

Photocatalytic Decarboxylative Alkylation of Cyclic Imine–BF3 Complexes: A Modular Route to Functionalized Azacycles

K Bhatt, A Adili, AH Tran, KM Elmallah… - Journal of the …, 2024 - ACS Publications
Alkyl radicals generated via an acridine photocatalyzed decarboxylation reaction of
feedstock carboxylic acids engage with a range of cyclic imine–BF3 complexes to provide α …

Cascade Cyclizations Triggered by Photochemically Generated Carbamoyl Radicals Derived from Alkyl Amines

GC Upreti, T Singh, D Chaudhary… - The Journal of Organic …, 2023 - ACS Publications
We report on a visible light-mediated cascade carbamoylation/cyclization of acrylamides
using dihydropyridyl carbamoyl donors derived from alkyl amines. Diversely selected …

Versatile, Modular, and General Strategy for the Synthesis of α-Amino Carbonyls

J Liu, MJ Gaunt - Journal of the American Chemical Society, 2024 - ACS Publications
Modulating the basicity of alkylamines is a crucial factor in drug design. Consequently,
alkylamines with a proximal amide, ester, or ketone have become privileged features in …

Photocatalytic synthesis of 2, 3-diamines from anilines and DIPEA via C–N bond cleavage and C–C bond formation

Y Meng, C Pan, N Liu, H Li, Z Liu, Y Deng, Z Wei… - Green …, 2024 - pubs.rsc.org
2, 3-Diamines are skeleton structures widely found in natural products and drug molecules
and can also be used as ligands in transition metal catalysis. A novel visible light-driven …

Taming photocatalysis in flow: easy and speedy preparation of α-aminoamide derivatives

RI Rodríguez, M Sicignano, MJ García, RG Enríquez… - Green …, 2022 - pubs.rsc.org
α-Aminoamides are reiterative molecular subunits in transcendental molecules, which bear
attractive functionalities for (bio) synthetic purposes. Herein, their preparation by harnessing …