The nematode Caenorhabditis elegans exhibits rapid senescence that is promoted by the
insulin/IGF-1 signalling (IIS) pathway via regulated processes that are poorly understood. IIS …

The aging process in semelparous and iteroparous species is different, but how different?
Death in semelparous organisms (eg, Pacific salmon) results from suicidal reproductive …

In some species of salmon, reproductive maturity triggers the development of massive
pathology resulting from reproductive effort, leading to rapid post-reproductive death. Such …

During aging, animals experience a decline in proteostasis activity, including loss of stress-
response activation, culminating in the accumulation of misfolded proteins and toxic …

Some of the most conspicuous aging phenotypes of C. elegans are related to post‐
reproductive production of vitellogenins (Vtg), which form yolk protein (YP) complexes after …

In some species of salmon, reproductive maturity triggers the development of massive
pathology resulting from reproductive effort, leading to rapid post-reproductive death. Such …

Adult C. elegans hermaphrodites exhibit severe senescent pathology that begins to develop
within days of reaching sexual maturity (;;;). For example, after depletion of self-sperm …

Some of the most conspicuous aging phenotypes of C. elegans are related to post-
reproductive production of vitellogenins (Vtg), which form yolk protein (YP) complexes after …

The nematode worm Caenorhabditis elegans has emerged as one of the premier model
systems for ageing research. Its use has led to the discovery of many biological mechanisms …