New approach methodologies (NAMs) are increasingly being used for regulatory decision making by agencies worldwide because of their potential to reliably and efficiently produce …
I Cattaneo, MC Astuto, M Binaglia, Y Devos… - Trends in Food Science …, 2023 - Elsevier
Abstract Background New Approach Methodologies (NAMs) comprise in silico and in vitro methods applied as alternative to animal testing. Even though NAMs are already fully …
J Blum, S Masjosthusmann, K Bartmann, F Bendt… - Chemosphere, 2023 - Elsevier
Developmental neurotoxicity (DNT) is a major safety concern for all chemicals of the human exposome. However, DNT data from animal studies are available for only a small …
M Keuper-Navis, M Walles, B Poller… - Pharmacological …, 2023 - Elsevier
Abstract Organ-on-chip (OoC) technology has led to in vitro models with many new possibilities compared to conventional in vitro and in vivo models. In this review, the …
T Hartung - ALTEX-Alternatives to animal experimentation, 2023 - altex.org
Four decades of the Human Genome Project and its consequences have shown how the entrepreneurial state, through significant investment into science, can drive scientific …
E Carnesecchi, I Langezaal, P Browne… - Regulatory Toxicology …, 2023 - Elsevier
Abstract In the European Union, the Chemicals Strategy for Sustainability (CSS) highlights the need to enhance the identification and assessment of substances of concern while …
LM Langan, M Paparella, N Burden… - Environmental …, 2024 - Wiley Online Library
In 2012, 20 key questions related to hazard and exposure assessment and environmental and health risks of pharmaceuticals and personal care products in the natural environment …
A Gruszecka-Kosowska, A Ampatzoglou… - International Journal of …, 2022 - mdpi.com
Research in the field of environmental sciences currently attracts a lot of attention. As the pollution of the environment is already pushing the earth beyond its homeostasis state …
EFSA's aim by 2030, is that the Agency and its partners will be equipped for the routine implementation of human health risk assessment to multiple chemicals, across EFSA's …