Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications

J Mondal, S Pillarisetti, V Junnuthula, M Saha… - Journal of Controlled …, 2023 - Elsevier
Exosomes are endosome-derived nanovesicles involved in cellular communication. They
are natural nanocarriers secreted by various cells, making them suitable candidates for …

Advances in drug delivery-based therapeutic strategies for renal fibrosis treatment

S Huang, H Lu, J Chen, C Jiang, G Jiang… - Journal of Materials …, 2024 - pubs.rsc.org
Renal fibrosis is the result of all chronic kidney diseases and is becoming a major global
health hazard. Currently, traditional treatments for renal fibrosis are difficult to meet clinical …

Plant‐derived vesicle‐like nanoparticles as promising biotherapeutic tools: Present and future

J Feng, Q Xiu, Y Huang, Z Troyer, B Li… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are heterogeneous, phospholipid bilayer‐enclosed biological
particles that regulate cell communication by molecular cargo delivery and surface …

Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

[HTML][HTML] Plant-derived exosome-like nanoparticles and their therapeutic activities

J Kim, S Li, S Zhang, J Wang - Asian journal of pharmaceutical sciences, 2022 - Elsevier
Nanotechnologies have been successfully applied to the treatment of various diseases.
Plant-derived exosome-like nanoparticles (PENs) are expected to become effective …

Technologies and standardization in research on extracellular vesicles

S Gandham, X Su, J Wood, AL Nocera, SC Alli… - Trends in …, 2020 - cell.com
Extracellular vesicles (EVs) are phospholipid bilayer membrane-enclosed structures
containing RNAs, proteins, lipids, metabolites, and other molecules, secreted by various …

[HTML][HTML] Lipids in exosomes: Current knowledge and the way forward

T Skotland, K Sandvig, A Llorente - Progress in lipid research, 2017 - Elsevier
Lipids are essential components of exosomal membranes, and it is well-known that specific
lipids are enriched in exosomes compared to their parent cells. In this review we discuss …

The lipid composition of extracellular vesicles: applications in diagnostics and therapeutic delivery

S Ghadami, K Dellinger - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Extracellular vesicles (EVs), including exosomes, with nanoscale sizes, biological origins,
various functions, and unique lipid and protein compositions have been introduced as …

Approaches to surface engineering of extracellular vesicles

M Richter, P Vader, G Fuhrmann - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) are cell-derived nanoparticles that are important mediators in
intercellular communication. This function makes them auspicious candidates for therapeutic …

[HTML][HTML] Harnessing strategies for enhancing diabetic wound healing from the perspective of spatial inflammation patterns

Y Cai, K Chen, C Liu, X Qu - Bioactive Materials, 2023 - Elsevier
Diabetic wound is a great threat to patient's health and lives. The refractory diabetic wound
shows spatial inflammation patterns, in which the early-wound pattern depicts a deprived …