Microglia in cancer therapy-related cognitive impairment

EM Gibson, M Monje - Trends in neurosciences, 2021 - cell.com
Millions of cancer survivors experience a persistent neurological syndrome that includes
deficits in memory, attention, information processing, and mental health. Cancer therapy …

Neuroimaging-based brain age estimation: A promising personalized biomarker in neuropsychiatry

D Sone, I Beheshti - Journal of Personalized Medicine, 2022 - mdpi.com
It is now possible to estimate an individual's brain age via brain scans and machine-learning
models. This validated technique has opened up new avenues for addressing clinical …

[HTML][HTML] Dose-dependent volume loss in subcortical deep grey matter structures after cranial radiotherapy

SHJ Nagtegaal, S David, MEP Philippens… - Clinical and translational …, 2021 - Elsevier
Background and purpose The relation between radiotherapy (RT) dose to the brain and
morphological changes in healthy tissue has seen recent increased interest. There already …

Neuroimaging based biotypes for precision diagnosis and prognosis in cancer-related cognitive impairment

SR Kesler, AM Henneghan, S Prinsloo, O Palesh… - Frontiers in …, 2023 - frontiersin.org
Cancer related cognitive impairment (CRCI) is commonly associated with cancer and its
treatments, yet the present binary diagnostic approach fails to capture the full spectrum of …

Cortical thinning in chemotherapy-treated older long-term breast cancer survivors

E Daniel, F Deng, SK Patel, MS Sedrak, H Kim… - Brain imaging and …, 2023 - Springer
Cognitive decline is an increasing issue for cancer survivors, especially for older adults, as
chemotherapy affects brain structure and function. The purpose of this single center study …

Four decades of chemotherapy-induced cognitive dysfunction: Comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events

A Dias-Carvalho, M Ferreira, R Ferreira, ML Bastos… - Archives of …, 2022 - Springer
Cognitive dysfunction has been one of the most reported and studied adverse effects of
cancer treatment, but, for many years, it was overlooked by the medical community …

[HTML][HTML] Blood and neuroimaging biomarkers of cognitive sequelae in breast cancer patients throughout chemotherapy: a systematic review

G Schroyen, J Vissers, A Smeets, CR Gillebert… - Translational …, 2022 - Elsevier
Breast cancer treatment can induce alterations in blood-and neuroimaging-based markers.
However, an overview of the predictive value of these markers for cognition is lacking for …

Neurocognitive impairment after hematopoietic stem cell transplant for hematologic malignancies: phenotype and mechanisms

RA Harrison, N Sharafeldin, JL Rexer, B Streck… - The …, 2021 - academic.oup.com
Hematopoietic stem cell transplant (HSCT) plays a central role in the treatment of
hematologic cancers. With the increasing survival of patients after HSCT, survivorship issues …

[HTML][HTML] The multifactorial model of cancer-related cognitive impairment

KR Oppegaard - Number 2/March 2023, 2023 - onf.ons.org
Problem Identification: Cancer-related cognitive impairment (CRCI) is common and is
associated with cancer and its treatments. Evidence suggests that the causes are …

Symptoms and experiences of frailty in lung cancer patients with chemotherapy: A mixed-method approach

L Duan, H Cui, W Zhang, S Wu - Frontiers in Oncology, 2022 - frontiersin.org
Objective The aim of this study was to explore the symptoms and experiences of frailty in
lung cancer patients treated with chemotherapy. Methods Quantitative and qualitative …