Alzheimer's disease (AD) is a neurodegenerative disorder characterized clinically by severe
cognitive deficits and pathologically by amyloid plaques, neuronal loss, and neurofibrillary …

Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …

Key points The ability to learn new motor skills is supported by plasticity in the structural and
functional organisation of the primary motor cortex in the human brain. Changes inhibitory to …

Abstract Magnetic Resonance Spectroscopy (MRS) allows for a non-invasive and non-
ionizing determination of in vivo tissue concentrations and metabolic turn-over rates of more …

Proton magnetic resonance spectroscopy is a powerful tool to investigate neurochemistry
and physiology in vivo. Recently researchers have started to use MRS to measure …

The balance of excitation and inhibition in neural circuits is hypothesized to be increased in
autism spectrum disorder, possibly mediated by altered signaling of the inhibitory …

While functional MRI (fMRI) localizes brain activation and deactivation, functional MRS
(fMRS) provides insights into the underlying metabolic conditions. There is much interest in …

Abnormalities of the glutamate system are increasingly implicated in schizophrenia but their
exact nature remains unknown. Proton magnetic resonance spectroscopy (1H-MRS), while …

Negative blood oxygenation–level dependent (BOLD) signal observed during task
execution in functional magnetic resonance imaging (fMRI) can be caused by different …

We investigated the relationship between neurochemical and hemodynamic responses as a
function of image contrast in the human primary visual cortex (V1). Simultaneously acquired …