Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …

There is no microbiological gold standard for childhood tuberculosis (TB) diagnosis. The
paucibacillary nature of the disease, challenges in sample collection in young children, and …

BACKGROUND: Diagnosis of tuberculosis should be improved in children infected with HIV
to reduce mortality. We developed prediction scores to guide antituberculosis treatment …

BACKGROUND AND OBJECTIVES Children experience high tuberculosis (TB)-related
mortality but causes of death among those with presumptive TB are poorly documented. We …

Background People living with human immunodeficiency virus (HIV) are more likely to
develop tuberculosis (TB), and their co-infection (HIV-TB) increases the risk of death. We …

There has been much recent progress on control of the tuberculosis (TB) and human
immunodeficiency virus (HIV) epidemics globally. However, advances in children have …

OBJECTIVE: To evaluate inter-reader agreement and diagnostic accuracy of chest
radiography (CXR) in the diagnosis of tuberculosis (TB) in children with human …

Background Children living with human immunodeficiency virus (HIV, CLWH) are at high
risk of tuberculosis (TB) and face poor outcomes, despite antiretroviral therapy (ART). We …

Background Management of HIV-infected children on a long-term basis is a challenge in
resource-limited countries. The aim of this study is to evaluate the long-term outcome and …