CT for treatment selection in acute ischemic stroke: a code stroke primer

CA Potter, AS Vagal, M Goyal, DB Nunez… - Radiographics, 2019 - pubs.rsna.org
CT is the primary imaging modality used for selecting appropriate treatment in patients with
acute stroke. Awareness of the typical findings, pearls, and pitfalls of CT image interpretation …

Extracellular vesicle–mediated delivery of circular RNA SCMH1 promotes functional recovery in rodent and nonhuman primate ischemic stroke models

L Yang, B Han, Z Zhang, S Wang, Y Bai, Y Zhang… - Circulation, 2020 - Am Heart Assoc
Background: Stroke is a leading cause of adult disability that can severely compromise the
quality of life of patients, yet no effective medication currently exists to accelerate …

Circular RNA TLK1 aggravates neuronal injury and neurological deficits after ischemic stroke via miR-335-3p/TIPARP

F Wu, B Han, S Wu, L Yang, S Leng, M Li… - Journal of …, 2019 - Soc Neuroscience
Circular RNAs (circRNAs) are expressed at high levels in the brain and are involved in
various CNS diseases. However, the potential role of circRNAs in ischemic stroke …

Time is brain: the stroke theory of relativity

CR Gomez - Journal of Stroke and Cerebrovascular Diseases, 2018 - Elsevier
Background Since the introduction of the philosophical tenet “Time is Brain!,” multiple lines
of research have demonstrated that other factors contribute to the degree of ischemic injury …

Neutrophil-to-lymphocyte ratio is a prognostic marker in acute ischemic stroke

J Xue, W Huang, X Chen, Q Li, Z Cai, T Yu… - Journal of Stroke and …, 2017 - Elsevier
Background Neutrophil-to-lymphocyte ratio is an independent predictor of mortality in
patients with acute ischemic stroke. However, it is uncertain whether neutrophil-to …

Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 …

KN Sheth, JJ Elm, BJ Molyneaux, H Hinson… - The Lancet …, 2016 - thelancet.com
Background Preclinical models of stroke have shown that intravenous glyburide reduces
brain swelling and improves survival. We assessed whether intravenous glyburide (RP …

Random forest-based prediction of stroke outcome

C Fernandez-Lozano, P Hervella, V Mato-Abad… - Scientific reports, 2021 - nature.com
We research into the clinical, biochemical and neuroimaging factors associated with the
outcome of stroke patients to generate a predictive model using machine learning …

Admission CT perfusion may overestimate initial infarct core: the ghost infarct core concept

S Boned, M Padroni, M Rubiera, A Tomasello… - Journal of …, 2017 - jnis.bmj.com
Background Identifying infarct core on admission is essential to establish the amount of
salvageable tissue and indicate reperfusion therapies. Infarct core is established on CT …

Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: the IAC study

S Yaghi, N Henninger, JA Giles, CL Guerrero… - Journal of Neurology …, 2021 - jnnp.bmj.com
Background and purpose A subset of ischaemic stroke patients with atrial fibrillation (AF)
have ischaemic stroke despite anticoagulation. We sought to determine the association …

Comparison of safety and clinical and radiographic outcomes in endovascular acute stroke therapy for proximal middle cerebral artery occlusion with intubation and …

MA Jumaa, F Zhang, G Ruiz-Ares, T Gelzinis, AM Malik… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—There is considerable heterogeneity in practice patterns
between sedation in the intubated state vs nonintubated state during endovascular acute …