The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

Abstract mRNA vaccines have emerged as a revolutionary tool to generate rapid and
precise immune responses against infectious diseases and cancers. Compared with …

The concept of mRNA-based vaccines emerged more than three decades ago.
Groundbreaking discoveries and technological advancements over the past 20 years have …

CircRNAs are a class of single-stranded RNAs with covalently linked head-to-tail topology.
In the decades since its initial discovery, their biogenesis, regulation, and function have …

The rapid development of two nucleoside-modified mRNA vaccines that are safe and highly
effective against coronavirus disease 2019 has transformed the vaccine field. The mRNA …

Treating immunosuppressive tumors represents a major challenge in cancer therapies.
Activation of STING signaling has shown remarkable potential to invigorate the …

Female reproductive health has traditionally been an underrepresented area of research in
the drug delivery sciences. This disparity is also seen in the emerging field of mRNA …

HSV-1 disease is a significant public health burden causing orofacial, genital, cornea, and
brain infection. We previously reported that a trivalent HSV-2 gC2, gD2, gE2 nucleoside …

Herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) are two of the
most prevalent human viruses worldwide. They are known to cause a variety of diseases …

Since the onset of the pandemic caused by severe acute respiratory syndrome coronavirus
2, messenger RNA (mRNA) vaccines have demonstrated outstanding performance. mRNA …