Therapeutic advances of targeting receptor tyrosine kinases in cancer
Receptor tyrosine kinases (RTKs), a category of transmembrane receptors, have gained
significant clinical attention in oncology due to their central role in cancer pathogenesis …
significant clinical attention in oncology due to their central role in cancer pathogenesis …
[HTML][HTML] TAM kinases as regulators of cell death
SM Post, M Andreeff, C DiNardo, JD Khoury… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Receptor Tyrosine Kinases are critical regulators of signal transduction that support
cell survival, proliferation, and differentiation. Dysregulation of normal Receptor Tyrosine …
cell survival, proliferation, and differentiation. Dysregulation of normal Receptor Tyrosine …
Correction of the tumor suppressor Salvador homolog-1 deficiency in tumors by lycorine as a new strategy in lung cancer therapy
Z Zhao, S Xiang, J Qi, Y Wei, M Zhang, J Yao… - Cell death & …, 2020 - nature.com
Abstract Salvador homolog-1 (SAV1) is a tumor suppressor required for activation of the
tumor-suppressive Hippo pathway and inhibition of tumorigenesis. SAV1 is defective in …
tumor-suppressive Hippo pathway and inhibition of tumorigenesis. SAV1 is defective in …