This review focuses on neurotrophins and their tyrosine kinase receptors, with an emphasis
on their relevance to the function and dysfunction in the human nervous system. It also deals …

Mood disorders and substance use disorder (SUD) are of immense medical and social
concern. Although significant progress on neuronal involvement in mood and reward …

Abstract L-DOPA-induced dyskinesia (LID) is a frequent adverse side effect of L-DOPA
treatment in Parkinson's disease (PD). Understanding the mechanisms underlying the …

Simple Summary Motor dysfunction is among the main symptoms of Parkinson's disease
(PD). This is closely linked to the loss of the neurotransmitter dopamine (DA) in the midbrain …

The dendritic arbour of striatal projection neurons (SPNs) is the primary anatomical site
where dopamine and glutamate inputs to the basal ganglia functionally interact to control …

Background: Depression is a prevalent nonmotor symptom in Parkinson disease and can
greatly reduce the quality of life for patients; the dopamine receptors found in glutamatergic …

Neurotrophins and their receptors are distinctly expressed during brain development and
play crucial roles in the formation, survival, and function of neurons in the nervous system …

Neurotrophins, particularly brain-derived neurotrophic factor (BDNF), act as key regulators of
neuronal development, survival, and plasticity. BDNF is necessary for neuronal and …

Major depressive disorder (MDD) and substance use disorder (SUD) are of immense
medical and social concerns. Although significant progress on neuronal involvement in …

Neurotrophins, particularly brain-derived neurotrophic factor (BDNF), act as key regulators of
neuronal development, survival and plasticity. In this review, we focus on the role of BDNF …