Direct and selective pharmacological disruption of the YAP–TEAD interface by IAG933 inhibits Hippo-dependent and RAS–MAPK-altered cancers
EA Chapeau, L Sansregret, GG Galli, P Chène… - Nature Cancer, 2024 - nature.com
The YAP–TEAD protein–protein interaction mediates YAP oncogenic functions downstream
of the Hippo pathway. To date, available YAP–TEAD pharmacologic agents bind into the …
of the Hippo pathway. To date, available YAP–TEAD pharmacologic agents bind into the …