Human pluripotent stem cell culture: considerations for maintenance, expansion, and therapeutics

KG Chen, BS Mallon, RDG McKay, PG Robey - Cell stem cell, 2014 - cell.com
Human pluripotent stem cells (hPSCs) provide powerful resources for application in
regenerative medicine and pharmaceutical development. In the past decade, various …

Material cues as potent regulators of epigenetics and stem cell function

SW Crowder, V Leonardo, T Whittaker… - Cell stem cell, 2016 - cell.com
Biophysical signals act as potent regulators of stem cell function, lineage commitment, and
epigenetic status. In recent years, synthetic biomaterials have been used to study a wide …

The electrical stimulation of carbon nanotubes to provide a cardiomimetic cue to MSCs

E Mooney, JN Mackle, DJP Blond, E O'Cearbhaill… - Biomaterials, 2012 - Elsevier
Once damaged, cardiac muscle has little intrinsic repair capability due to the poor
regeneration potential of remaining cardiomyocytes. One method of overcoming this issue is …

Peptide-based self-assembled monolayers (SAMs): what peptides can do for SAMs and vice versa

C Redondo-Gómez, P Parreira, MCL Martins… - Chemical Society …, 2024 - pubs.rsc.org
Self-assembled monolayers (SAMs) represent highly ordered molecular materials with
versatile biochemical features and multidisciplinary applications. Research on SAMs has …

Biomimetic supramolecular designs for the controlled release of growth factors in bone regeneration

HS Azevedo, I Pashkuleva - Advanced drug delivery reviews, 2015 - Elsevier
The extracellular matrix (ECM) of tissues is an assembly of insoluble macromolecules that
specifically interact with soluble bioactive molecules and regulate their distribution and …

Bacteriophage-based biomaterials for tissue regeneration

B Cao, Y Li, T Yang, Q Bao, M Yang, C Mao - Advanced drug delivery …, 2019 - Elsevier
Bacteriophage, also called phage, is a human-safe bacteria-specific virus. It is a
monodisperse biological nanostructure made of proteins (forming the outside surface) and …

Receptor-ligand interactions: Advanced biomedical applications

I Guryanov, S Fiorucci, T Tennikova - Materials Science and Engineering …, 2016 - Elsevier
Receptor-ligand interactions (RLIs) are at the base of all biological events occurring in living
cells. The understanding of interactions between complementary macromolecules in …

Scanning probe-enabled nanocombinatorics define the relationship between fibronectin feature size and stem cell fate

LR Giam, MD Massich, L Hao… - Proceedings of the …, 2012 - National Acad Sciences
We report the development of a powerful analytical method that utilizes a tilted elastomeric
pyramidal pen array in the context of a scanning probe lithography experiment to rapidly …

Molecular engineering of the TGF-β signaling pathway

Z Zi - Journal of molecular biology, 2019 - Elsevier
Transforming growth factor beta (TGF-β) is an important growth factor that plays essential
roles in regulating tissue development and homeostasis. Dysfunction of TGF-β signaling is a …

Advances in high-resolution microscopy for the study of intracellular interactions with biomaterials

CS Hansel, MN Holme, S Gopal, MM Stevens - Biomaterials, 2020 - Elsevier
The study of sophisticated biomaterials and their cellular targets requires visualization
methods with exquisite spatial and temporal resolution to discern cell organelles and …