Tree balance plays an important role in phylogenetics and other research areas, which is
why several indices to measure tree balance have been introduced over the years …

The clonal evolution model of cancer was developed in the 1950s–1970s and became
central to cancer biology in the twenty-first century, largely through studies of cancer …

Characterizing the mode—the way, manner or pattern—of evolution in tumours is important
for clinical forecasting and optimizing cancer treatment. Sequencing studies have inferred …

Birth–death models are stochastic processes describing speciation and extinction through
time and across taxa and are widely used in biology for inference of evolutionary timescales …

Background The combined effects of biological variability and measurement-related errors
on cancer sequencing data remain largely unexplored. However, the spatio-temporal …

Phylogenetic trees are believed to contain a wealth of information on diversification
processes. However, comparing phylogenetic trees is not straightforward due to their high …

Phylogenetic networks play an important role in evolutionary biology as, other than
phylogenetic trees, they can be used to accommodate reticulate evolutionary events such as …

The processes that generate biodiversity start on a microevolutionary scale, where each
individual's history can impact the species' history. This manuscript presents a theoretical …

Rooted and ranked phylogenetic trees are mathematical objects that are useful in modelling
hierarchical data and evolutionary relationships with applications to many fields such as …

Geographic space is a fundamental dimension of evolutionary change, determining how
individuals disperse and interact with each other. Consequently, space has an important …