Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

A healthy brain is protected by the blood–brain barrier (BBB), which is formed by the
endothelial cells that line brain capillaries. The BBB plays an extremely important role in …

Sonobiopsy is an emerging technology that combines focused ultrasound (FUS) with
microbubbles to enrich circulating brain disease-specific biomarkers for noninvasive …

Non-invasive drug delivery across the blood–brain barrier (BBB) represents a significant
advancement in treating neurological diseases. The BBB is a tightly packed layer of …

Piezoelectric ultrasonic transducers have shown great potential in biomedical applications
due to their high acoustic-to-electric conversion efficiency and large power capacity. The …

Drug delivery to the brain is crucial in the treatment for central nervous system disorders.
While significant progress has been made in recent years, there are still major challenges in …

As a highly selective and semi-permeable barrier that separates the circulating blood from
the brain and central nervous system (CNS), the blood-brain barrier (BBB) plays a critical …

Introduction The tight structure of the blood–brain barrier severely limits the level of drug
therapy for central nervous system disorders. In this study, a novel composite delivery …

The prevalence of Alzheimer's disease (AD) is increasing globally due to population aging.
However, effective clinical treatment strategies for AD still remain elusive. The mechanisms …

The efficacy of neurotherapeutic drugs hinges on their ability to traverse the blood-brain
barrier and access the brain, which is crucial for treating or alleviating neurodegenerative …