Management of patients on non–vitamin K antagonist oral anticoagulants in the acute care and periprocedural setting: a scientific statement from the American Heart …

AN Raval, JE Cigarroa, MK Chung, LJ Diaz-Sandoval… - Circulation, 2017 - Am Heart Assoc
Non–vitamin K oral anticoagulants (NOACs) are now widely used as alternatives to warfarin
for stroke prevention in atrial fibrillation and management of venous thromboembolism. In …

[HTML][HTML] Hemodialysis for the treatment of dabigatran‐associated bleeding: a case report and systematic review

C Chai‐Adisaksopha, C Hillis, W Lim… - Journal of Thrombosis …, 2015 - Elsevier
Background Dabigatran, a direct thrombin inhibitor, is effective for the treatment of venous
thromboembolism and the prevention of stroke and systemic embolism resulting from atrial …

Direct-acting oral anticoagulants and their reversal agents—an update

SA Kustos, PS Fasinu - Medicines, 2019 - mdpi.com
Background: Over the last ten years, a new class of drugs, known as the direct-acting oral
anticoagulants (DOACs), have emerged at the forefront of anticoagulation therapy. Like the …

Cancer-associated thrombosis: investigating the role of new oral anticoagulants

M Franchini, C Bonfanti, G Lippi - Thrombosis Research, 2015 - Elsevier
Venous thromboembolism (VTE) is a common complication of cancer and has a significant
impact on morbidity and mortality in patients with malignancies. Low molecular weight …

Potential antidotes for reversal of old and new oral anticoagulants

D Suryanarayan, S Schulman - Thrombosis research, 2014 - Elsevier
The prescription of new oral anticoagulants is on the rise. As opposed to vitamin K
antagonists and heparins the new agents have single targets in the coagulation cascade …

Comparison of novel oral anticoagulants versus vitamin K antagonists in patients with chronic kidney disease

Z Harel, MM Sood, J Perl - Current opinion in nephrology and …, 2015 - journals.lww.com
Comparison of novel oral anticoagulants versus vitamin K ant... : Current Opinion in
Nephrology and Hypertension Comparison of novel oral anticoagulants versus vitamin K …

An evaluation of oral dabigatran etexilate pharmacokinetics and pharmacodynamics in hemodialysis

JAS Wilson, KB Goralski, SD Soroka… - The Journal of …, 2014 - Wiley Online Library
Dabigatran etexilate represents a possible improved alternative to warfarin for
anticoagulation in hemodialysis patients with atrial fibrillation (AF). The objective was to …

Antithrombotic and antiplatelet drug toxicity

DB Liss, ME Mullins - Critical Care Clinics, 2021 - criticalcare.theclinics.com
Significant progress has been made in the development of medications to prevent
thrombosis and platelet aggregation. These drugs target specific components of the …

Comparison of intermittent and continuous extracorporeal treatments for the enhanced elimination of dabigatran

J Bouchard, M Ghannoum, A Bernier-Jean… - Clinical …, 2015 - Taylor & Francis
Context. Severe bleeding associated with dabigatran frequently requires intensive care
management. An antidote is currently unavailable and data reporting the effect of dialysis on …

Reversal and resumption of anticoagulants in patients with anticoagulant-associated intracerebral hemorrhage

J Yang, J Jing, S Chen, X Liu, J Wang, C Pan… - European Journal of …, 2024 - Springer
The use of anticoagulants has become more frequent due to the progressive aging
population and increased thromboembolic events. Consequently, the proportion of …