The microbiota and the gut–liver axis in primary sclerosing cholangitis

JR Hov, TH Karlsen - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
Primary sclerosing cholangitis (PSC) offers unique opportunities to explore the gut–liver axis
owing to the close association between liver disease and colonic inflammation. It is well …

[HTML][HTML] Aging unconventionally: γδ T cells, iNKT cells, and MAIT cells in aging

A Kurioka, P Klenerman - Seminars in Immunology, 2023 - Elsevier
Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …

MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles

T Kammann, C Cai, T Sekine, E Mouchtaridi… - Science …, 2024 - science.org
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that recognize
microbial riboflavin pathway metabolites presented by evolutionarily conserved MR1 …

Mechanisms of microbe-immune system dialogue within the skin

N Lunjani, S Ahearn-Ford, FS Dube, C Hlela… - Genes & …, 2021 - nature.com
The prevalence and severity of dermatological conditions such as atopic dermatitis have
increased dramatically during recent decades. Many of the factors associated with an …

Unconventional T cells and kidney disease

H Kaminski, L Couzi, M Eberl - Nature Reviews Nephrology, 2021 - nature.com
Unconventional T cells are a diverse and underappreciated group of relatively rare
lymphocytes that are distinct from conventional CD4+ and CD8+ T cells, and that mainly …

Pathogenic role of IL-17 and therapeutic targeting of IL-17F in psoriatic arthritis and spondyloarthropathies

G Sánchez-Rodríguez, L Puig - International journal of molecular …, 2023 - mdpi.com
The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial
roles in host defence against microbial organisms and the development of inflammatory …

[HTML][HTML] Skin barrier immunology from early life to adulthood

A Trompette, ND Ubags - Mucosal Immunology, 2023 - Elsevier
Our skin has a unique barrier function, which is imperative for the body's protection against
external pathogens and environmental insults. Although interacting closely and sharing …

Emerging applications of nanotechnology in context to immunology: A comprehensive review

H Mobeen, M Safdar, A Fatima, S Afzal… - … in Bioengineering and …, 2022 - frontiersin.org
Numerous benefits of nanotechnology are available in many scientific domains. In this
sense, nanoparticles serve as the fundamental foundation of nanotechnology. Recent …

Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis

SK Wyatt-Johnson, HN Kersey, JF Codocedo… - Journal of …, 2023 - Springer
Background Neuroinflammation is an important feature of Alzheimer's disease (AD).
Understanding which aspects of the immune system are important in AD may lead to new …

[HTML][HTML] Role of MAIT cells in gastrointestinal tract bacterial infections in humans: More than a gut feeling

Y Zheng, F Han, A Ho, Y Xue, Z Wu, X Chen… - Mucosal …, 2023 - Elsevier
Mucosa-associated invariant T (MAIT) cells are the largest population of unconventional T
cells in humans. These antimicrobial T cells are poised with rapid effector responses …