Noble metals in medicine: Latest advances
History shows that metal-based drugs and remedies have been known and used since very
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
ancient times. For example, silver was employed in the treatment of wounds and ulcers …
Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
Synthesis and structure of new binuclear ruthenium (II) arene benzil bis (benzoylhydrazone) complexes: investigation on antiproliferative activity and apoptosis …
MSM Kasim, S Sundar, R Rengan - Inorganic chemistry frontiers, 2018 - pubs.rsc.org
A series of binuclear ruthenium (II) arene benzil bis (benzoylhydrazone) complexes (1–6) of
the common composition [(η6-arene) 2Ru2 (L) Cl2](arene= benzene or p-cymene; L= benzil …
the common composition [(η6-arene) 2Ru2 (L) Cl2](arene= benzene or p-cymene; L= benzil …
Hydroxyquinoline derived vanadium (IV and V) and copper (II) complexes as potential anti-tuberculosis and anti-tumor agents
Several mixed ligand vanadium and copper complexes were synthesized containing 8-
hydroxyquinoline (8HQ) and a ligand such as picolinato (pic−), dipicolinato (dipic 2−) or a …
hydroxyquinoline (8HQ) and a ligand such as picolinato (pic−), dipicolinato (dipic 2−) or a …
Influence of Indole-N Substitution of Thiosemicarbazones in Cationic Ru(II)(η6-Benzene) Complexes on Their Anticancer Activity
Indole thiosemicarbazones (TSCs) and their complexes are known to possess various
biological activities. The variation in anticancer activity with different indole-N substituents of …
biological activities. The variation in anticancer activity with different indole-N substituents of …
Water-soluble mono-and binuclear Ru (η6-p-cymene) complexes containing indole thiosemicarbazones: synthesis, DFT modeling, biomolecular interactions, and in …
Indole thiosemicarbazone ligands were prepared from indole-3-carboxaldehyde and N-(un)
substituted thiosemicarbazide. The Ru (η6-p-cymene) complexes [Ru (η6-p-cymene)(HL1) …
substituted thiosemicarbazide. The Ru (η6-p-cymene) complexes [Ru (η6-p-cymene)(HL1) …
RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo
Ruthenium (II) complexes are currently considered a viable alternative to the widely used
platinum complexes as efficient anticancer agents. We herein present the synthesis and …
platinum complexes as efficient anticancer agents. We herein present the synthesis and …
Synthesis, cytotoxicity and docking studies (with SARS-CoV-2) of water-soluble binuclear Ru-p-cymene complex holding indole thiosemicarbazone ligand
A water-soluble binuclear organometallic Ru-p-cymene complex [Ru (η 6-p-cymene)(η 2-L)]
2 (1) was prepared from (E)-2-((1H-indol-3-yl) methylene)-N-phenylhydrazine-1 …
2 (1) was prepared from (E)-2-((1H-indol-3-yl) methylene)-N-phenylhydrazine-1 …
Derivation of structure–activity relationships from the anticancer properties of ruthenium (II) arene complexes with 2-aryldiazole ligands
M Martinez-Alonso, N Busto, FA Jalon… - Inorganic …, 2014 - ACS Publications
The ligands 2-pyridin-2-yl-1 H-benzimidazole (HL1), 1-methyl-2-pyridin-2-ylbenzimidazole
(HL2), and 2-(1 H-imidazol-2-yl) pyridine (HL3) and the proligand 2-phenyl-1 H …
(HL2), and 2-(1 H-imidazol-2-yl) pyridine (HL3) and the proligand 2-phenyl-1 H …
Recent advancements in coordination compounds and their potential clinical application in the management of diseases: An up-to-date review
Coordination compounds-based drugs are crucial in targeting various diseases due to their
distinct structural order. They also show a significant role in biological systems, including …
distinct structural order. They also show a significant role in biological systems, including …