MALDI-MSI towards multimodal imaging: challenges and perspectives

M Tuck, F Grélard, L Blanc, N Desbenoit - Frontiers in Chemistry, 2022 - frontiersin.org
Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …

Spatial analysis of drug absorption, distribution, metabolism, and toxicology using mass spectrometry imaging

ML Spruill, M Maletic-Savatic, H Martin, F Li… - Biochemical …, 2022 - Elsevier
Mass spectrometry imaging (MSI) is emerging as a powerful analytical tool for detection,
quantification, and simultaneous spatial molecular imaging of endogenous and exogenous …

Seeing plants as never before

L Borisjuk, P Horn, K Chapman, PM Jakob… - New …, 2023 - Wiley Online Library
Imaging has long supported our ability to understand the inner life of plants, their
development, and response to a dynamic environment. While optical microscopy remains …

A review on recent machine learning applications for imaging mass spectrometry studies

A Jetybayeva, N Borodinov, AV Ievlev… - Journal of Applied …, 2023 - pubs.aip.org
Imaging mass spectrometry (IMS) is a powerful analytical technique widely used in biology,
chemistry, and materials science fields that continue to expand. IMS provides a qualitative …

Correlative chemical imaging and spatial chemometrics delineate Alzheimer plaque heterogeneity at high spatial resolution

PM Wehrli, J Ge, W Michno, S Koutarapu, A Dreos… - JACS au, 2023 - ACS Publications
We present a novel, correlative chemical imaging strategy based on multimodal matrix-
assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) …

Spatial correlation of water distribution and fine structure of arabinoxylans in the developing wheat grain

M Fanuel, F Grélard, L Foucat, C Alvarado… - Carbohydrate …, 2022 - Elsevier
This study was to investigate the distribution of water and arabinoxylan structures in growing
wheat grain using two complementary imaging techniques, magnetic resonance …

Probe‐based mass spectrometry approaches for single‐cell and single‐organelle measurements

DC Castro, P Chan‐Andersen… - Mass Spectrometry …, 2024 - Wiley Online Library
Exploring the chemical content of individual cells not only reveals underlying cell‐to‐cell
chemical heterogeneity but is also a key component in understanding how cells combine to …

Fusing ToF‐SIMS Images for Spatial‐Spectral Resolution Enhancement using a Convolutional Neural Network

W Gardner, DA Winkler, R Maliki… - Advanced Materials …, 2022 - Wiley Online Library
Hyperspectral data sets generated by time‐of‐flight secondary ion mass spectrometry (ToF‐
SIMS) contain valuable spatial‐spectral information characterizing the distribution of atomic …

The journey towards clinical adoption of MALDI‐MS‐based imaging proteomics: from current challenges to future expectations

I Piga, F Magni, A Smith - FEBS letters, 2024 - Wiley Online Library
Among the spatial omics techniques available, mass spectrometry imaging (MSI) represents
one of the most promising owing to its capability to map the distribution of hundreds of …

Synchrotron Based X-ray Microtomography Reveals Cellular Morphological Features of Developing Wheat Grain

D Legland, C Alvarado, E Badel, F Guillon, A King… - Applied Sciences, 2022 - mdpi.com
Wheat is one of the most important crops in the world, mainly used for human consumption
and animal feed. To overcome the increasing demand in wheat production, it is necessary to …